Mutant allele-specific imbalance modulates prognostic impact of KRAS mutations in colorectal adenocarcinoma and is associated with worse overall survival (Q28258483)

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English	Mutant allele-specific imbalance modulates prognostic impact of KRAS mutations in colorectal adenocarcinoma and is associated with worse overall survival	scientific article

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scholarly article

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Mutant allele-specific imbalance modulates prognostic impact of KRAS mutations in colorectal adenocarcinoma and is associated with worse overall survival (English)

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1 reference

based on heuristic

inferred from title

colorectal adenocarcinoma

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based on heuristic

inferred from title

author name string

D J Hartman

1

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J M Davison

2

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T J Foxwell

3

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M N Nikiforova

4

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S I Chiosea

5

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language of work or name

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publication date

15 October 2012

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International Journal of Cancer

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131

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8

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1810-7

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Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study

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KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: practical application of patient selection

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Prognostic significance of alterations in KRAS isoforms KRAS-4A/4B and KRAS mutations in colorectal carcinoma.

1 reference

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Specific TP53 and/or Ki-ras mutations as independent predictors of clinical outcome in sporadic colorectal adenocarcinomas: results of a 5-year Gruppo Oncologico dell'Italia Meridionale (GOIM) prospective study.

1 reference

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Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab

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American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy

1 reference

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Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells

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Wildtype Kras2 can inhibit lung carcinogenesis in mice

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LOH of chromosome 12p correlates with Kras2 mutation in non-small cell lung cancer

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Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines

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A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells

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Oncogenic activating mutations are associated with local copy gain

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Higher dosage of the epidermal growth factor receptor mutant allele in lung adenocarcinoma correlates with younger age, stage IV at presentation, and poorer survival.

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KRAS mutant allele-specific imbalance in lung adenocarcinoma

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EGFR fluorescence in situ hybridization-positive lung adenocarcinoma: incidence of coexisting KRAS and BRAF mutations.

1 reference

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Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer

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Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer

1 reference

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Loss of heterozygosity of Kras2 gene on 12p12-13 in Chinese colon carcinoma patients

1 reference

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Integrative approach for prioritizing cancer genes in sporadic colon cancer.

1 reference

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Pathogenesis and consequences of uniparental disomy in cancer

1 reference

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Frequent occurrence of uniparental disomy in colorectal cancer

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In Situ Evidence of KRAS Amplification and Association With Increased p21 Levels in Non–Small Cell Lung Carcinoma

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21 January 2018

Identifiers

10.1002/IJC.27461

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