Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha (Q28259513)

GOA release 2020-03-11

11

G L Semenza

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John D. Gearhart

8

object named as

J D Gearhart

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author name string

N V Iyer

1

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L E Kotch

2

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F Agani

3

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S W Leung

4

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E Laughner

5

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R H Wenger

6

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M Gassmann

7

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A M Lawler

9

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A Y Yu

The murine Sim-2 gene product inhibits transcription by active repression and functional interference

10

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language of work or name

English

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publication date

15 January 1998

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published in

Genes & Development

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volume

12

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page(s)

149-62

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issue

2

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cites work

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Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

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A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

20 March 2017

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Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

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In vivo expression of mRNAs encoding hypoxia-inducible factor 1

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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

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Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

20 March 2017

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

20 March 2017

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

20 March 2017

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Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL

20 March 2017

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cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt)

20 March 2017

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Purification and characterization of hypoxia-inducible factor 1

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Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

7 April 2017

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7 April 2017

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Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

7 April 2017

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7 April 2017

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On respiratory impairment in cancer cells

7 April 2017

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7 April 2017

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V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression.

7 April 2017

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29 September 2017

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The mouse gene for hypoxia-inducible factor-1alpha--genomic organization, expression and characterization of an alternative first exon and 5' flanking sequence

29 September 2017

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HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels

29 September 2017

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Absolute requirement of aryl hydrocarbon receptor nuclear translocator protein for gene activation by hypoxia

29 September 2017

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29 September 2017

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Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha

29 September 2017

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Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells

29 September 2017

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The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development

29 September 2017

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Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes

29 September 2017

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GATA-binding transcription factors in hematopoietic cells

29 September 2017

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Production of homozygous mutant ES cells with a single targeting construct

29 September 2017

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Reversion of transformed glycolysis to normal by inhibition of protein synthesis in rat kidney cells infected with temperature-sensitive mutant of Rous sarcoma virus

29 September 2017

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Oxygen(es) and the hypoxia-inducible factor-1.

29 September 2017

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The hypoxic response: huffing and HIFing

2 June 2018

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Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer

2 June 2018

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Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

2 June 2018

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The mouse gene for vascular endothelial growth factor. Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences.

27 November 2018

1 reference

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Post-transcriptional regulation of vascular endothelial growth factor by hypoxia.

27 November 2018

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27 November 2018

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Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia.

27 November 2018

1 reference

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Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells.

27 November 2018

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Vascular endothelial cell lineage-specific promoter in transgenic mice

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Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

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Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

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Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

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Ethanol-induced teratogenesis: free radical damage as a possible mechanism

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Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1

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Identifiers

DOI

10.1101/GAD.12.2.149

1 reference

413108

413108

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1 reference

1 reference