Insertional mutagenesis in mice: new perspectives and tools (Q28259871)

The knockout mouse project

Europe PubMed Central

title

Insertional mutagenesis in mice: new perspectives and tools (English)

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2

David A Largaespada

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Corey M Carlson

series ordinal

1

object named as

Corey M Carlson

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language of work or name

English

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publication date

July 2005

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published in

Nature Reviews Genetics

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volume

6

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issue

7

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page(s)

568-80

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cites work

1 reference

The European dimension for the mouse genome mutagenesis program

21 April 2017

1 reference

Insertion of Inhbb into the Inhba locus rescues the Inhba-null phenotype and reveals new activin functions

21 April 2017

1 reference

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

21 April 2017

1 reference

Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

21 April 2017

1 reference

Suppression of nonsense-mediated mRNA decay permits unbiased gene trapping in mouse embryonic stem cells

21 April 2017

1 reference

The functional landscape of mouse gene expression

21 April 2017

1 reference

Creation of genome-wide protein expression libraries using random activation of gene expression

21 April 2017

1 reference

Engineering mouse chromosomes with Cre-loxP: range, efficiency, and somatic applications

21 April 2017

1 reference

The Bloom's syndrome gene product is homologous to RecQ helicases

21 April 2017

1 reference

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

21 April 2017

1 reference

Large-scale analysis of the yeast genome by transposon tagging and gene disruption

21 April 2017

1 reference

Regulated transposition of a fish transposon in the mouse germ line

21 April 2017

1 reference

Functional genetic analysis of mouse chromosome 11

21 April 2017

1 reference

High-resolution genome-wide mapping of transposon integration in mammals

21 April 2017

1 reference

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

21 April 2017

1 reference

The Bloom's syndrome helicase suppresses crossing over during homologous recombination

21 April 2017

1 reference

An efficient recombination system for chromosome engineering in Escherichia coli

21 April 2017

1 reference

Transcription start regions in the human genome are favored targets for MLV integration

21 April 2017

1 reference

Sequence interpretation. Functional annotation of mouse genome sequences

21 April 2017

1 reference

21 January 2018

Mouse ENU mutagenesis

1 reference

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

21 January 2018

1 reference

Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome.

21 January 2018

1 reference

Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles.

21 January 2018

1 reference

Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes.

21 January 2018

1 reference

Mutagenic insertion and chromosome engineering resource (MICER).

21 January 2018

1 reference

A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice

21 January 2018

1 reference

Engineering chromosomal rearrangements in mice

21 January 2018

1 reference

Hunting with traps: genome-wide strategies for gene discovery and functional analysis

21 January 2018

1 reference

Gene-trap mutagenesis: past, present and beyond

21 January 2018

1 reference

A public gene trap resource for mouse functional genomics

21 January 2018

1 reference

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells

21 January 2018

1 reference

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

21 January 2018

1 reference

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

21 January 2018

1 reference

Targeting survival: integration site selection by retroviruses and LTR-retrotransposons

21 January 2018

1 reference

Functional analysis of secreted and transmembrane proteins critical to mouse development.

21 January 2018

1 reference

Defining brain wiring patterns and mechanisms through gene trapping in mice.

21 January 2018

1 reference

Gene-trap expression screening to identify endothelial-specific genes

21 January 2018

1 reference

A gene trap vector system for identifying transcriptionally responsive genes.

21 January 2018

1 reference

Inducible gene trapping with drug-selectable markers and Cre/loxP to identify developmentally regulated genes

21 January 2018

1 reference

Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis.

21 January 2018

1 reference

Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

21 January 2018

1 reference

Efficient biallelic mutagenesis with Cre/loxP-mediated inter-chromosomal recombination

21 January 2018

1 reference

A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.

21 January 2018

1 reference

21 January 2018

1 reference

Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cells

21 January 2018

1 reference

Genome-wide phenotype analysis in ES cells by regulated disruption of Bloom's syndrome gene

21 January 2018

1 reference

GAL4 system in Drosophila: a fly geneticist's Swiss army knife

21 January 2018

1 reference

A modular misexpression screen in Drosophila detecting tissue-specific phenotypes

21 January 2018

1 reference

The Drosophila melanogaster DmRAD54 gene plays a crucial role in double-strand break repair after P-element excision and acts synergistically with Ku70 in the repair of X-ray damage

21 January 2018

1 reference

High frequency retrotransposition in cultured mammalian cells

21 January 2018

1 reference

A highly active synthetic mammalian retrotransposon

21 January 2018

1 reference

More active human L1 retrotransposons produce longer insertions

21 January 2018

1 reference

Identification of autonomous IAP LTR retrotransposons mobile in mammalian cells.

21 January 2018

1 reference

APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses.

21 January 2018

1 reference

Transposable element in fish.

21 January 2018

1 reference

The medaka fish Tol2 transposable element can undergo excision in human and mouse cells.

21 January 2018

1 reference

Transposition of the Tol2 element, an Ac-like element from the Japanese medaka fish Oryzias latipes, in mouse embryonic stem cells

21 January 2018

1 reference

Genome-wide insertional mutagenesis in human cells by the Drosophila mobile element Minos

21 January 2018

1 reference

In vivo transposition of Minos, a Drosophila mobile element, in mammalian tissues

21 January 2018

1 reference

Transposition of the Drosophila hydei Minos transposon in the mouse germ line.

21 January 2018

1 reference

Transposon Tc1 of the nematode Caenorhabditis elegans jumps in human cells.

21 January 2018

1 reference

The Himar1 mariner transposase cloned in a recombinant adenovirus vector is functional in mammalian cells

21 January 2018

1 reference

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

21 January 2018

1 reference

Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells

21 January 2018

1 reference

Mammalian germ-line transgenesis by transposition.

21 January 2018

1 reference

Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system

21 January 2018

1 reference

In vivo correction of murine tyrosinemia type I by DNA-mediated transposition.

21 January 2018

1 reference

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

21 January 2018

1 reference

Integration and long-term expression in xenografted human glioblastoma cells using a plasmid-based transposon system

21 January 2018

1 reference

Transposition and gene disruption in the male germline of the mouse

21 January 2018

1 reference

Efficient chromosomal transposition of a Tc1/mariner- like transposon Sleeping Beauty in mice.

21 January 2018

1 reference

Characterization of Sleeping Beauty transposition and its application to genetic screening in mice

21 January 2018

1 reference

Retroviral insertional mutagenesis as a strategy to identify cancer genes

21 January 2018

1 reference

Germline transmission of RNAi in mice

21 January 2018

1 reference

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

21 January 2018

1 reference

A resource for large-scale RNA-interference-based screens in mammals.

21 January 2018

1 reference

Large-scale mutational analysis for the annotation of the mouse genome

21 January 2018

1 reference

Conditional control of gene expression in the mouse

21 January 2018

1 reference

Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates

21 January 2018

1 reference

Enhancement of Sleeping Beauty transposition by CpG methylation: possible role of heterochromatin formation

21 January 2018

1 reference

The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition

21 January 2018

1 reference

Nonhomologous-End-Joining Factors Regulate DNA Repair Fidelity during Sleeping Beauty Element Transposition in Mammalian Cells

21 January 2018

1 reference

Healing the wounds inflicted by sleeping beauty transposition by double-strand break repair in mammalian somatic cells.

21 January 2018

1 reference

Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

21 January 2018

1 reference

Capturing genes encoding membrane and secreted proteins important for mouse development

31 March 2020

1 reference

Efficient Cre-loxP-induced mitotic recombination in mouse embryonic stem cells

31 March 2020

1 reference

Molecular evidence that homologous recombination occurs in proliferating human somatic cells

31 March 2020

1 reference

Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene

31 March 2020

1 reference

Enhanced tumor formation in mice heterozygous for Blm mutation

31 March 2020

1 reference

Target-selected gene inactivation in Caenorhabditis elegans by using a frozen transposon insertion mutant bank

31 March 2020

1 reference

Transposon tagging and molecular analysis of the maize regulatory locus opaque-2

31 March 2020

1 reference

Gene disruptions using P transposable elements: an integral component of the Drosophila genome project

31 March 2020

1 reference

P-element-mediated enhancer detection: a versatile method to study development in Drosophila.

31 March 2020

1 reference

Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector

31 March 2020

1 reference

P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila

31 March 2020

1 reference

Insertional mutagenesis of the Drosophila genome with single P elements

31 March 2020

1 reference

A mouse model of human L1 retrotransposition

31 March 2020

1 reference

Genomic deletions created upon LINE-1 retrotransposition

31 March 2020

1 reference

Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1638

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

829624

1010395356

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829624

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference