Testosterone deficiency, insulin resistance and the metabolic syndrome (Q28262608)

Nature Reviews Endocrinology

Europe PubMed Central

title

Testosterone deficiency, insulin resistance and the metabolic syndrome (English)

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Michael Zitzmann

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language of work or name

English

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publication date

December 2009

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published in

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volume

5

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issue

12

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page(s)

673-81

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cites work

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Left ventricular dysfunction in Klinefelter syndrome is associated to insulin resistance, abdominal adiposity and hypogonadism

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Increased mortality in Klinefelter syndrome.

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In the elderly, interleukin-6 plasma levels and the -174G>C polymorphism are associated with the development of cardiovascular disease

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Tumor necrosis factor-alpha and interleukin-1beta increase the Fas-mediated apoptosis of human osteoblasts

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Testosterone suppresses the response of the hypothalamic-pituitary-adrenal axis to interleukin-6

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Sex hormones modulate inflammatory mediators produced by macrophages

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The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men.

31 March 2020

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Inverse relationship between serum levels of interleukin-1beta and testosterone in men with stable coronary artery disease

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Androgen-replacement therapy depresses the ex vivo production of inflammatory cytokines by circulating antigen-presenting cells in aging type-2 diabetic men with partial androgen deficiency

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Gonadotropin treatment restoresin vitrointerleukin-1β and tumour necrosis factor-α production by stimulated peripheral blood mononuclear cells from patients with idiopathic hypogonadotropic hypogonadism

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Endogenous progesterone and the exogenous progestin norethisterone enanthate are associated with a proinflammatory profile in healthy men.

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The effect of testosterone replacement therapy on adipocytokines and C-reactive protein in hypogonadal men with type 2 diabetes.

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Physiological, pharmacological, and nutritional regulation of circulating adiponectin concentrations in humans

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Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency

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Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes

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Dose-dependent effects of testosterone on regional adipose tissue distribution in healthy young men.

31 March 2020

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Testosterone therapy prevents gain in visceral adipose tissue and loss of skeletal muscle in nonobese aging men.

31 March 2020

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Testosterone treatment in elderly men with subnormal testosterone levels improves body composition and BMD in the hip.

31 March 2020

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Concurrent improvement of the metabolic syndrome and lower urinary tract symptoms upon normalisation of plasma testosterone levels in hypogonadal elderly men.

31 March 2020

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Investigation, treatment, and monitoring of late-onset hypogonadism in males: ISA, ISSAM, EAU, EAA, and ASA recommendations

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https://api.crossref.org/works/10.1038%2FNRENDO.2009.212

Effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men: a randomized controlled trial

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Testosterone substitution normalizes elevated serum leptin levels in hypogonadal men.

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Insulin resistance in patients with Klinefelter's syndrome and idiopathic gonadotropin deficiency

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Leptin and androgens in male obesity: evidence for leptin contribution to reduced androgen levels

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Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men

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Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency

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Lower endogenous androgens predict central adiposity in men

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Androgens stimulate endothelial progenitor cells through an androgen receptor-mediated pathway

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Expression of functional leptin receptors in rodent Leydig cells

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