A novel centromere monospecific serum to a human autoepitope on the histone H3-like protein CENP-A (Q28262670)

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J Figueroa

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C Iglesias

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M Ortíz

Autoantibody to centromere (kinetochore) in scleroderma sera

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language of work or name

English

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publication date

23 January 1998

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published in

FEBS Letters

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volume

422

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issue

1

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page(s)

5-9

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cites work

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Three human chromosomal autoantigens are recognized by sera from patients with anti-centromere antibodies

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Fractionation and initial characterization of the kinetochore from mammalian metaphase chromosomes

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Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen

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CENP-B is a highly conserved mammalian centromere protein with homology to the helix-loop-helix family of proteins

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Molecular cloning of an intronless gene for the hamster centromere antigen CENP-B.

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A human centromere protein, CENP-B, has a DNA binding domain containing four potential alpha helices at the NH2 terminus, which is separable from dimerizing activity

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CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate

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Sequence homologies and linkage group conservation of the human and mouse Cenpc genes

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Sheep CENPB and CENPC genes show a high level of sequence similarity and conserved synteny with their human homologs

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Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere

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Assembly of CENP-A into centromeric chromatin requires a cooperative array of nucleosomal DNA contact sites

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A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles and with histones

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Purification of the centromere-specific protein CENP-A and demonstration that it is a distinctive histone

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

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Formation of de novo centromeres and construction of first-generation human artificial microchromosomes

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Anticentromere antibody specific to human cells directed against the CENP-B autoantigen

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Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis

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DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

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A charged segment mainly composed of basic amino acids forms an autoepitope of CENP-A

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Human germinal centre B cells inhibit mitogen-induced proliferation of mantle zone B cells

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Visualization of centromere proteins CENP-B and CENP-C on a stable dicentric chromosome in cytological spreads

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