Review: When is an antioxidant not an antioxidant? A review of novel actions and reactions of vitamin C (Q28263084)

Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer

Europe PubMed Central

title

Review: When is an antioxidant not an antioxidant? A review of novel actions and reactions of vitamin C (English)

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Tiago L Duarte

1

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author name string

Joseph Lunec

series ordinal

2

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language of work or name

English

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publication date

July 2005

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published in

Free Radical Research

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volume

39

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page(s)

671-86

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issue

7

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cites work

1 reference

https://api.crossref.org/works/10.1080/10715760500104025

Oxygen radicals and signaling

21 April 2017

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Vitamin C and genomic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

The physiological role of dehydroascorbic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

A family of mammalian Na+-dependent L-ascorbic acid transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Mammalian facilitative hexose transporters mediate the transport of dehydroascorbic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Variation in the expression and/or phosphorylation of the human low molecular weight stress protein during in vitro cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Differential effects of glucose on dehydroascorbic acid transport and intracellular ascorbate accumulation in astrocytes and skeletal myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Vitamin C recycling is enhanced in the adaptive response to leptin-induced oxidative stress in keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Measurement of DNA oxidation in human cells by chromatographic and enzymic methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Ascorbic acid protects against endogenous oxidative DNA damage in human sperm

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Vitamin C exhibits pro-oxidant properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Vitamin C supplementation decreases oxidative DNA damage in mononuclear blood cells of smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Does vitamin C have a pro-oxidant effect?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Ascorbate on cell growth and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Sodium ascorbate potentiates the growth inhibitory effect of certain agents on neuroblastoma cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Vitamin C in alternative cancer treatment: historical background

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Vegetables, fruit, and cancer prevention: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Antioxidant supplements for prevention of gastrointestinal cancers: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

How does ascorbic acid prevent endothelial dysfunction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Induction of antioxidant stress proteins in vascular endothelial and smooth muscle cells: protective action of vitamin C against atherogenic lipoproteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Antioxidant vitamins and prevention of cardiovascular disease: laboratory, epidemiological and clinical trial data

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Regulation of procollagen synthesis and processing during ascorbate-induced extracellular matrix accumulation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

In vitro oxidation of ascorbic acid and its prevention by GSH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

In the absence of catalytic metals ascorbate does not autoxidize at pH 7: ascorbate as a test for catalytic metals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Hydrogen peroxide. Ubiquitous in cell culture and in vivo?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

L-Ascorbic acid induces apoptosis in acute myeloid leukemia cells via hydrogen peroxide-mediated mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Ascorbate and alpha-tocopherol prevent apoptosis induced by serum removal independent of Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

The in vitro cytotoxicity of ascorbate depends on the culture medium used to perform the assay and involves hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Ascorbic acid maintenance in HaCaT cells prevents radical formation and apoptosis by UV-B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

From cells to ageing: a review of models and mechanisms of cellular senescence and their impact on human ageing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Oxidants, oxidative stress and the biology of ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Oxidative stress and gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Ascorbic acid in the 21st century - more than a simple antioxidant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Regulation of collagenase-3 and osteocalcin gene expression by collagen and osteopontin in differentiating MC3T3-E1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Functional roles of the tissue inhibitor of metalloproteinase 3 (TIMP-3) during ascorbate-induced differentiation of osteoblastic MC3T3-E1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

L-ascorbic acid stimulates expression of smooth muscle-specific markers in smooth muscle cells both in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Role of reactive oxygen species and phosphatidylinositol 3-kinase in cardiomyocyte differentiation of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Changes of gene expression profiles during neuronal differentiation of central nervous system precursors treated with ascorbic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Effect of ascorbic acid on hepatic vasoregulatory gene expression during polymicrobial sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Function and activation of NF-kappa B in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025

Does vitamin C have a pro-oxidant effect?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10715760500104025