Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75 (Q28263591)

4

object named as

Yves Engelborghs

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Alan N Engelman

5

object named as

Alan Engelman

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Peter Cherepanov

2

object named as

Peter Cherepanov

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author name string

Goedele Maertens

Journal of Biological Chemistry

1

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language of work or name

English

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publication date

6 August 2004

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published in

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volume

279

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issue

32

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page(s)

33421-9

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cites work

Nucleocytoplasmic transport: the soluble phase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Sequence requirements for nuclear location of simian virus 40 large-T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

The nucleoplasmin nuclear location sequence is larger and more complex than that of SV-40 large T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

A novel receptor-mediated nuclear protein import pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

A nuclear localization domain in the hnRNP A1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Nuclear targeting of proteins: how many different signals?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Protein import into the nucleus: an integrated view

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import substrate at nuclear pore complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Kinetic analysis of translocation through nuclear pore complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Catalysis of guanine nucleotide exchange of Ran by RCC1 and stimulation of hydrolysis of Ran-bound GTP by Ran-GAP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

NTF2 mediates nuclear import of Ran.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

The importin beta/importin 7 heterodimer is a functional nuclear import receptor for histone H1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Importin alpha can migrate into the nucleus in an importin beta- and Ran-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

The importin-beta binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Subcellular localization of feline immunodeficiency virus integrase and mapping of its karyophilic determinant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Identification of critical amino acid residues in human immunodeficiency virus type 1 IN required for efficient proviral DNA formation at steps prior to integration in dividing and nondividing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Spatial and temporal dynamics of two alternatively spliced regulatory factors, lens epithelium-derived growth factor (ledgf/p75) and p52, in the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

LEDGF, a survival factor, activates stress-related genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Transcriptional regulation of the antioxidant protein 2 gene, a thiol-specific antioxidant, by lens epithelium-derived growth factor to protect cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

A knowledge base for predicting protein localization sites in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Finding nuclear localization signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

RanGAP1 induces GTPase activity of nuclear Ras-related Ran

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Importin beta can mediate the nuclear import of an arginine-rich nuclear localization signal in the absence of importin alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

The role of mononuclear phagocytes in HTLV-III/LAV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Characterization of the nuclear import pathway for HIV-1 integrase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Functional analysis of HIV-1 Vpr: identification of determinants essential for subcellular localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Efficient HIV-1 replication can occur in the absence of the viral matrix protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

HIV-1 infection requires a functional integrase NLS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Wild-type levels of nuclear localization and human immunodeficiency virus type 1 replication in the absence of the central DNA flap

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

A synthetic peptide bearing the HIV-1 integrase 161-173 amino acid residues mediates active nuclear import and binding to importin alpha: characterization of a functional nuclear localization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Intracellular transport of human immunodeficiency virus type 1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

Cellular Distribution and Karyophilic Properties of Matrix, Integrase, and Vpr Proteins from the Human and Simian Immunodeficiency Viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

RanBP1 is crucial for the release of RanGTP from importin β-related nuclear transport factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404700200

21 January 2018

Identifiers

DOI

10.1074/JBC.M404700200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

15163664

1 reference

Consolidated OpenCitations Corpus – April 2017