Role of CCL2 (MCP-1) in traumatic brain injury (TBI): evidence from severe TBI patients and CCL2-/- mice (Q28268523)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20029451%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Role of CCL2 (MCP-1) in traumatic brain injury (TBI): evidence from severe TBI patients and CCL2-/- mice (English)

1 reference

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15 January 2020

main subject

brain

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traumatic brain injury

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0 references

4

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Maria Cristina Morganti-Kossmann

15 January 2020

5

1 reference

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15 January 2020

author name string

Bridgette D Semple

1

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15 January 2020

Nicole Bye

2

1 reference

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15 January 2020

Mario Rancan

3

1 reference

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15 January 2020

language of work or name

English

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publication date

23 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20029451%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cerebral Blood Flow & Metabolism

15 January 2020

published in

1 reference

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15 January 2020

volume

30

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15 January 2020

issue

4

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15 January 2020

page(s)

769-782

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describes a project that uses

15 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2949175/fullTextXML

inferred from PubMed Central ID database lookup

cites work

MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis

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The temporal expression, cellular localization, and inhibition of the chemokines MIP-2 and MCP-1 after traumatic brain injury in the rat

20 March 2017

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Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

20 March 2017

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Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.

20 March 2017

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Blood monocytes consist of two principal subsets with distinct migratory properties

20 March 2017

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Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks

7 April 2017

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Modulation of immune response by head injury

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Monocyte recruitment and myelin removal are delayed following spinal cord injury in mice with CCR2 chemokine receptor deletion

29 September 2017

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Role of cerebral inflammation after traumatic brain injury: a revisited concept

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Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury

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Inflammation in traumatic brain injury: role of cytokines and chemokines

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Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice

29 September 2017

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Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1.

29 September 2017

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Distribution, cellular localization and functional role of CCR2 chemokine receptors in adult rat brain.

29 September 2017

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Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury

2 June 2018

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An experimental model of closed head injury in mice: pathophysiology, histopathology, and cognitive deficits

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Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat.

2 June 2018

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Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration.

2 June 2018

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Overexpression of monocyte chemoattractant protein 1 in the brain exacerbates ischemic brain injury and is associated with recruitment of inflammatory cells.

21 January 2018

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21 January 2018

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Differential and time-dependent expression of monocyte chemoattractant protein-1 mRNA by astrocytes and macrophages in rat brain: effects of ischemia and peripheral lipopolysaccharide administration.

21 January 2018

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21 January 2018

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Monocyte chemoattractant protein-1 deficiency is protective in a murine stroke model.

21 January 2018

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21 January 2018

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Ablation of the chemokine monocyte chemoattractant protein-1 delays retrograde neuronal degeneration, attenuates microglial activation, and alters expression of cell death molecules.

21 January 2018

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Serum IL-8 and MCP-1 concentration do not identify patients with enlarging contusions after traumatic brain injury.

21 January 2018

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21 January 2018

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21 January 2018

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Multiplex Assessment of Cytokine and Chemokine Levels in Cerebrospinal Fluid following Severe Pediatric Traumatic Brain Injury: Effects of Moderate Hypothermia

21 January 2018

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The chemokine receptor CCR2 mediates the binding and internalization of monocyte chemoattractant protein-1 along brain microvessels.

21 January 2018

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Upregulation of ICAM-1 and MCP-1 but not of MIP-2 and sensorimotor deficit in response to traumatic axonal injury in rats.

27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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12 December 2020

Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines

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12 December 2020

Early and specific expression of monocyte chemoattractant protein-1 in the thalamus induced by cortical injury

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12 December 2020

Ccr2 regulates the level of MCP-1/CCL2 in vitro and at inflammatory sites and controls T cell activation in response to alloantigen

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12 December 2020

Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain

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12 December 2020

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1038/JCBFM.2009.262

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20029451%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20029451%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

2 references