Oral renin inhibitors (Q28269879)

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Language	Label	Description	Also known as
English	Oral renin inhibitors	scientific article

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Europe PubMed Central

Oral renin inhibitors (English)

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Jan A. Staessen

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Jan A Staessen

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Yan Li

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Tom Richart

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publication date

21 October 2006

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368

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9545

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1449-56

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Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

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Intermediate but not low doses of aspirin can suppress angiotensin-converting enzyme inhibitor-induced cough

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Renin inhibition: what are the therapeutic opportunities?

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Pharmacology of renin inhibitors and their application to the treatment of hypertension

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Pathways for angiotensin II generation in intact human tissue: evidence from comparative pharmacological interruption of the renin system

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The preparation, purification, and amino acid sequence of a polypeptide renin substrate

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Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats

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Antibodies to renin as proof of the pathogenesis of sustained renal hypertension

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PRODUCTION OF ANTIRENIN TO HOMOLOGOUS RENIN AND ITS EFFECT OF EXPERIMENTAL RENAL HYPERTENSION

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Active immunization against renin in normotensive marmoset

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Inhibition of the renin-angiotensinogen reaction by pepstatin

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Analysis of structure-activity relationships in renin substrate analogue inhibitory peptides.

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Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine

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Renin inhibitors. Dipeptide analogues of angiotensinogen incorporating transition-state, nonpeptidic replacements at the scissile bond

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A study of the renin inhibitor H142 in man

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Effects of a specific and long-acting renin inhibitor in the marmoset

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Angiotensin II suppression in humans by the orally active renin inhibitor Aliskiren (SPP100): comparison with enalapril

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Pharmacological investigations of a new renin inhibitor in normal sodium-unrestricted volunteers

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Clinical pharmacokinetics and efficacy of renin inhibitors

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Hemodynamics, biochemical effects, and pharmacokinetics of the renin inhibitor remikiren in healthy human subjects

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Dose-Dependent Effects of the Renin Inhibitor Zankiren HCl After a Single Oral Dose in Mildly Sodium-Depleted Normotensive Subjects

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Piperidine renin inhibitors: from leads to drug candidates

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Direct micro-radioimmunoassay of the new renin inhibitor CGP 60536.

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Structure-based design of aliskiren, a novel orally effective renin inhibitor

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Comparative effects of three different potent renin inhibitors in primates

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Effects of chronic infusion of renin inhibitor A-64662 in sodium-depleted monkeys

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New inhibitors of human renin tested in vitro and in vivo in the anaesthetized baboon

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Renal and endocrine responses to a renin inhibitor, enalkiren, in normal humans

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Hemodynamic and humoral effects of the new renin inhibitor enalkiren in normal humans

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Responses to an orally active renin inhibitor, remikiren (Ro 42-5892), after controlled salt depletion in humans

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Renal vascular responses to renin inhibition with zankiren in men*

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Effect of the renin response during renin inhibition: oral Ro 42-5892 in normal humans

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Effects of an orally active renin inhibitor, Ro 42-5892, in patients with essential hypertension.

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Efficacy and tolerability of the renin inhibitor Ro 42-5892 in patients with hypertension

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Renal and systemic effects of the renin inhibitor remikiren in patients with essential hypertension

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Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption

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Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren

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Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients

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1 reference

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1 reference

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Nonparallel effects of renin inhibitor treatment on plasma renin activity and angiotensins I and II in hypertensive subjects. An assay-related artifact

1 reference

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based on heuristic

inferred from DOI database lookup

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1 reference

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Tissue renin-angiotensin systems and reproduction

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Renin inhibitor and converting enzyme inhibitors suppress vascular angiotensin II

1 reference

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Major role of the renin angiotensin system in the neointima formation after vascular injury in guinea pigs

1 reference

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Carotid Intima-Media Thickness and Antihypertensive Treatment

1 reference

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Renal vascular and biochemical responses to systemic renin inhibition in dogs at low renal perfusion pressure

1 reference

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Effects of blocking the angiotensin II receptor, converting enzyme, and renin activity on the renal hemodynamics of normotensive guinea pigs.

1 reference

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Responses to converting enzyme and renin inhibition. Role of angiotensin II in humans

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Renal and systemic effects of continued treatment with renin inhibitor remikiren in hypertensive patients with normal and impaired renal function

1 reference

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7 January 2021

based on heuristic

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Distribution of remikiren, a potent orally active inhibitor of human renin, in laboratory animals

1 reference

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Hemodynamic Effects of Angiotensin and Renin Inhibition in Dogs with Acute Left Ventricular Failure

1 reference

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1 reference

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7 January 2021

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1 reference

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7 January 2021

based on heuristic

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1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7

7 January 2021

based on heuristic

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1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7

7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7

7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7

7 January 2021

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Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7

7 January 2021

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Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7

7 January 2021

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Blood pressure reduction and cardiovascular prevention: an update including the 2003-2004 secondary prevention trials

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7 January 2021

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7 January 2021

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1 reference

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7 January 2021

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10.1016/S0140-6736(06)69442-7

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