Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides (Q28271259)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802619%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides (English)

1 reference

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4-hydroxy-6-(2-oxoheptyl)pyran-2-one

8 February 2020

main subject

1 reference

1 reference

1 reference

1 reference

1 reference

3,5,7-trioxododecanoyl-CoA(4-)

ChEBI ID

66962

1 reference

1 reference

4-hydroxy-6-pentylpyran-2-one

ChEBI ID

67081

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802619%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Steve J Gagne

1

1 reference

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8 February 2020

Enwu Liu

3

1 reference

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8 February 2020

Zakia Boubakir

4

1 reference

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8 February 2020

Shawn M Clark

5

1 reference

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8 February 2020

Jonathan E Page

6

1 reference

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8 February 2020

language of work or name

English

0 references

publication date

16 July 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802619%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

8 February 2020

published in

1 reference

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8 February 2020

volume

109

1 reference

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8 February 2020

issue

31

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8 February 2020

page(s)

12811-12816

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The draft genome and transcriptome of Cannabis sativa

8 February 2020

cites work

1 reference

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Crystal Structure and Catalytic Mechanism of 4-Methylmuconolactone Methylisomerase

20 March 2017

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Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa

20 March 2017

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20 March 2017

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Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketides

20 March 2017

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The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L

20 March 2017

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The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis.

20 March 2017

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Resorcinolic Lipids, the Natural Non-isoprenoid Phenolic Amphiphiles and Their Biological Activity

20 March 2017

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20 March 2017

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Structure and mechanism of the evolutionarily unique plant enzyme chalcone isomerase

20 March 2017

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The hexanoyl-CoA precursor for cannabinoid biosynthesis is formed by an acyl-activating enzyme in Cannabis sativa trichomes.

20 March 2017

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Smoked cannabis for chronic neuropathic pain: a randomized controlled trial

29 September 2017

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Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway

29 September 2017

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Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa

29 September 2017

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The Bet v 1 fold: an ancient, versatile scaffold for binding of large, hydrophobic ligands

29 September 2017

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Nature's assembly line: biosynthesis of simple phenylpropanoids and polyketides

29 September 2017

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Characterization of a heat-stable protein with antimicrobial activity from Arabidopsis thaliana

29 September 2017

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Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa.

29 September 2017

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Chemical constituents of marijuana: the complex mixture of natural cannabinoids

29 September 2017

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Structural elucidation of chalcone reductase and implications for deoxychalcone biosynthesis.

29 September 2017

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The structural basis of the thermostability of SP1, a novel plant (Populus tremula) boiling stable protein

29 September 2017

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Structural and functional analysis of tetracenomycin F2 cyclase from Streptomyces glaucescens. A type II polyketide cyclase.

29 September 2017

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Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation

29 September 2017

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Characterization of SP1, a stress-responsive, boiling-soluble, homo-oligomeric protein from aspen

29 September 2017

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29 September 2017

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Ectopic expression of the minimal whiE polyketide synthase generates a library of aromatic polyketides of diverse sizes and shapes

29 September 2017

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29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Alkylresorcylic acid synthesis by type III polyketide synthases from rice Oryza sativa

21 January 2018

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Octaketide-producing type III polyketide synthase from Hypericum perforatum is expressed in dark glands accumulating hypericins

21 January 2018

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Crystal structure of the protein from gene At3g17210 of Arabidopsis thaliana

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22802619

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1200330109

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802619%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

ADS bibcode

2012PNAS..10912811G

0 references

1 reference

2 references

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8 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802619%20AND%20SRC:MED&resulttype=core&format=json