The histone demethylase UTX enables RB-dependent cell fate control (Q28272073)

1

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Miao-Chih Tsai

2

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Gino Poulin

3

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Adam S Adler

4

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Shuzhen Chen

5

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Helen Liu

6

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Yang Shi

7

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Howard Y Chang

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

8

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language of work or name

English

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publication date

15 February 2010

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published in

Genes & Development

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volume

24

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issue

4

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page(s)

327-32

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cites work

1 reference

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The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

20 March 2017

1 reference

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A histone H3 lysine 27 demethylase regulates animal posterior development

20 March 2017

1 reference

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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

20 March 2017

1 reference

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Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

20 March 2017

1 reference

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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

20 March 2017

1 reference

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Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth

20 March 2017

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

20 March 2017

1 reference

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

20 March 2017

1 reference

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HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family

20 March 2017

1 reference

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Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

20 March 2017

1 reference

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SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron

20 March 2017

1 reference

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Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark

20 March 2017

1 reference

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Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

7 April 2017

1 reference

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The polycomb group protein EZH2 is involved in progression of prostate cancer

7 April 2017

1 reference

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Polycomb silencers control cell fate, development and cancer

7 April 2017

1 reference

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A network-based analysis of systemic inflammation in humans

7 April 2017

1 reference

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Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes

7 April 2017

1 reference

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Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

Genome-wide views of chromatin structure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

Update on the olfactory receptor (OR) gene superfamily

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

Cellular mechanisms of tumour suppression by the retinoblastoma gene.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

Protocadherin family: diversity, structure, and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

A transcriptional program mediating entry into cellular quiescence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

The SynMuv genes of Caenorhabditis elegans in vulval development and beyond

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

A module map showing conditional activity of expression modules in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

NURD-complex genes antagonise Ras-induced vulval development in Caenorhabditis elegans

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731

27 November 2018

Identifiers

DOI

10.1101/GAD.1882610

1 reference

release_bgevvi2brfb45d2eshe5nhnrj4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bgevvi2brfb45d2eshe5nhnrj4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

1 reference

PubMed publication ID

20123895

1 reference