The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9 (Q28272159)

Cell death protein 3 subunit p17 CELE_C48D1.2

GOA release 2020-03-11

1 reference

Apoptosis regulator ced-9 CELE_T07C4.8

GOA release 2020-03-11

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Gene identification using the yeast two-hybrid system

GOA release 2020-03-11

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2

H R Horvitz

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author name string

B Conradt

series ordinal

1

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language of work or name

English

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publication date

15 May 1998

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published in

Cell

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volume

93

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issue

4

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page(s)

519-29

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cites work

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7 January 2021

The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation

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7 January 2021

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

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7 January 2021

Role of CED-4 in the activation of CED-3.

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7 January 2021

Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coli

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7 January 2021

A common binding site mediates heterodimerization and homodimerization of Bcl-2 family members

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7 January 2021

Genetic control of programmed cell death in the nematode C. elegans.

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7 January 2021

Mechanisms and Functions of Cell Death

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7 January 2021

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7 January 2021

The mec-7 beta-tubulin gene of Caenorhabditis elegans is expressed primarily in the touch receptor neurons

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7 January 2021

Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K

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7 January 2021

The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein

1 reference

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7 January 2021

Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2.

1 reference

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7 January 2021

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

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7 January 2021

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

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7 January 2021

The genetics of programmed cell death in the nematode Caenorhabditis elegans.

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7 January 2021

A peptide sequence from Bax that converts Bcl-2 into an activator of apoptosis

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7 January 2021

Functional dissection of the human Bc12 protein: sequence requirements for inhibition of apoptosis

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7 January 2021

harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)

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7 January 2021

Programmed cell death: a missing link is found

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7 January 2021

CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9.

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7 January 2021

Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

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7 January 2021

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7 January 2021

Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2.

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7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

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7 January 2021

Caspases: killer proteases

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7 January 2021

Mutational analysis of the interacting cell death regulators CED-9 and CED-4.

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7 January 2021

Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins

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7 January 2021

Social controls on cell survival and cell death

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7 January 2021

Errors of homeostasis and deregulated apoptosis

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7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

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7 January 2021

Caenorhabditis elegans CED-4 stimulates CED-3 processing and CED-3-induced

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7 January 2021

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities

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7 January 2021

An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor

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7 January 2021

Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

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7 January 2021

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

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7 January 2021

The embryonic cell lineage of the nematode Caenorhabditis elegans

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7 January 2021

CED-4--the third horseman of apoptosis

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7 January 2021

BID: a novel BH3 domain-only death agonist

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7 January 2021

Life, death, and the pursuit of apoptosis.

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7 January 2021

Interaction and regulation of subcellular localization of CED-4 by CED-9

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7 January 2021

Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9.

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7 January 2021

Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor

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7 January 2021

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

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7 January 2021

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

1 reference

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7 January 2021

Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2

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7 January 2021

BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity

1 reference

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7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

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7 January 2021

end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos

1 reference

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7 January 2021