The biosynthesis and regulation of bacterial prodiginines (Q28274333)

Nature Reviews Microbiology

Europe PubMed Central

title

The biosynthesis and regulation of bacterial prodiginines (English)

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2

Peter C Fineran

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author name string

Neil R Williamson

series ordinal

1

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Finian J Leeper

series ordinal

3

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George P C Salmond

series ordinal

4

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language of work or name

English

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publication date

December 2006

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published in

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volume

4

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issue

12

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page(s)

887-99

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cites work

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Phosphate availability regulates biosynthesis of two antibiotics, prodigiosin and carbapenem, in Serratia via both quorum-sensing-dependent and -independent pathways

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Pharmaceutically active secondary metabolites of microorganisms

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The prodigiosins, proapoptotic drugs with anticancer properties

31 March 2020

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Synthesis and immunosuppressive activity of novel prodigiosin derivatives

31 March 2020

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T-cell specific immunosuppression by prodigiosin isolated from Serratia marcescens

31 March 2020

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Effective prevention of lethal acute graft-versus-host disease by combined immunosuppressive therapy with prodigiosin and cyclosporine A.

31 March 2020

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Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin

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Prodigiosin induces apoptosis by acting on mitochondria in human lung cancer cells

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Mitochondria-mediated apoptosis operating irrespective of multidrug resistance in breast cancer cells by the anticancer agent prodigiosin

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Antimetastatic effect of prodigiosin through inhibition of tumor invasion

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Synthesis, proton-affinity and anti-cancer properties of the prodigiosin-group natural products

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DNA interaction and dual topoisomerase I and II inhibition properties of the anti-tumor drug prodigiosin

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The core structures of roseophilin and the prodigiosin alkaloids define a new class of protein tyrosine phosphatase inhibitors

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Diversity of antifungal and plant-associated Serratia plymuthica strains.

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Potent in vitro anticancer activity of metacycloprodigiosin and undecylprodigiosin from a sponge-derived actinomycete Saccharopolyspora sp. nov.

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Genetic analysis of absB, a Streptomyces coelicolor locus involved in global antibiotic regulation

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Identification of Streptomyces coelicolor genes involved in regulation of antibiotic synthesis

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The bldC developmental locus of Streptomyces coelicolor encodes a member of a family of small DNA-binding proteins related to the DNA-binding domains of the MerR family.

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SigB, an RNA polymerase sigma factor required for osmoprotection and proper differentiation of Streptomyces coelicolor.

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Characterization of spaA, a Streptomyces coelicolor gene homologous to a gene involved in sensing starvation in Escherichia coli.

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abaA, a new pleiotropic regulatory locus for antibiotic production in Streptomyces coelicolor

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Pleiotropic effects of cAMP on germination, antibiotic biosynthesis and morphological development in Streptomyces coelicolor.

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Influence of Serratia marcescens Pigmentation on Cell Concentrations in Aerosols Produced by Bursting Bubbles

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Prodigiosin Synthesis in Mutants of Serratia marcesens

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Cloning and expression in Escherichia coli of Serratia marcescens genes encoding prodigiosin biosynthesis

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Identifiers

DOI

10.1038/NRMICRO1531

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

480511

1002108693

0 references

480511

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference