The antigenic structure of the HIV gp120 envelope glycoprotein (Q28274698)

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object named as

P D Kwong

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author name string

E Desjardins

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R W Sweet

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J Robinson

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W A Hendrickson

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J G Sodroski

Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III.

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language of work or name

English

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publication date

18 June 1998

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published in

Nature

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volume

393

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page(s)

705-11

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issue

6686

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cites work

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The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

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T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

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HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

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Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer

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CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

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CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

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HTLV-III/LAV-neutralizing antibodies to an E. coli-produced fragment of the virus envelope

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Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120

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Dimeric association and segmental variability in the structure of human CD4

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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Analysis of the interaction of antibodies with a conserved enzymatically deglycosylated core of the HIV type 1 envelope glycoprotein 120

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7 January 2021

Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding

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7 January 2021

Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.

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7 January 2021

Exploration of antigenic variation in gp120 from clades A through F of human immunodeficiency virus type 1 by using monoclonal antibodies

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7 January 2021

Characterization of molecularly cloned simian-human immunodeficiency viruses causing rapid CD4+ lymphocyte depletion in rhesus monkeys

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7 January 2021

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

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7 January 2021