The IDO1 selective inhibitor epacadostat enhances dendritic cell immunogenicity and lytic ability of tumor antigen-specific T cells (Q28275608)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27192116%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

The IDO1 selective inhibitor epacadostat enhances dendritic cell immunogenicity and lytic ability of tumor antigen-specific T cells (English)

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2 April 2020

1 reference

Massimo Claudio Fantini

2

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2 April 2020

15

Jeffrey Schlom

1 reference

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2 April 2020

10

James L Gulley

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2 April 2020

author name string

Caroline Jochems

1

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2 April 2020

Romaine I Fernando

3

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2 April 2020

Anna R Kwilas

4

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2 April 2020

Renee N Donahue

5

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2 April 2020

Lauren M Lepone

6

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2 April 2020

Italia Grenga

7

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2 April 2020

Young-Seung Kim

8

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2 April 2020

Martin W Brechbiel

9

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2 April 2020

Ravi A Madan

11

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2 April 2020

Christopher R Heery

12

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2 April 2020

James W Hodge

13

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2 April 2020

Robert Newton

14

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2 April 2020

Kwong Y Tsang

16

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2 April 2020

language of work or name

English

0 references

publication date

1 June 2016

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2 April 2020

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2 April 2020

volume

7

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2 April 2020

page(s)

37762-37772

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2 April 2020

issue

25

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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

2 April 2020

cites work

1 reference

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Inhibition of T cell proliferation by macrophage tryptophan catabolism

20 March 2017

1 reference

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1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase

20 March 2017

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Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality

20 March 2017

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Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy.

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Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8(+) T cells directly within the tumor microenvironment

29 September 2017

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Induction of hepatitis B virus surface antigen-specific cytotoxic T lymphocytes can be up-regulated by the inhibition of indoleamine 2, 3-dioxygenase activity

29 September 2017

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Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4.

29 September 2017

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L-kynurenine-induced apoptosis in human NK cells is mediated by reactive oxygen species

29 September 2017

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Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators

29 September 2017

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An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells

29 September 2017

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Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors

29 September 2017

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Induction of indoleamine 2, 3-dioxygenase by death receptor activation contributes to apoptosis of melanoma cells via mitochondrial damage-dependent ROS accumulation

29 September 2017

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The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase

29 September 2017

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Hemoglobin induces the expression of indoleamine 2,3-dioxygenase in dendritic cells through the activation of PI3K, PKC, and NF-kappaB and the generation of reactive oxygen species

29 September 2017

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IDO activates regulatory T cells and blocks their conversion into Th17-like T cells

29 September 2017

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Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells.

29 September 2017

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Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.

29 September 2017

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The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival

27 November 2018

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Oxygen radical-induced natural killer cell dysfunction: role of myeloperoxidase and regulation by serotonin

27 November 2018

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27 November 2018

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Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation

27 November 2018

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12 December 2020

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

1 reference

12 December 2020

Melanoma immunotherapy: a battle against radicals?

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12 December 2020

Expression of indoleamine 2, 3-dioxygenase and the recruitment of Foxp3-expressing regulatory T cells in the development and progression of uterine cervical cancer

1 reference

12 December 2020

Indoleamine 2,3-dioxygenase, Tregs and cancer

1 reference

12 December 2020

Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial

1 reference

12 December 2020

Analyses of 123 Peripheral Human Immune Cell Subsets: Defining Differences with Age and between Healthy Donors and Cancer Patients Not Detected in Analysis of Standard Immune Cell Types.

1 reference

12 December 2020

Induction of apoptosis in NK cells by monocyte-derived reactive oxygen metabolites

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12 December 2020

Identifiers

DOI

10.18632/ONCOTARGET.9326

2 references

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2 April 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27192116%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

2 references