Gut hormones and the regulation of energy homeostasis (Q28278826)

Monogenic obesity in humans

Europe PubMed Central

title

Gut hormones and the regulation of energy homeostasis (English)

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Kevin G Murphy

1

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author name string

Stephen R Bloom

series ordinal

2

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language of work or name

English

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publication date

14 December 2006

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published in

Nature

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volume

444

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page(s)

854-9

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issue

7121

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cites work

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Ghrelin action in the brain controls adipocyte metabolism

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Ghrelin and the short- and long-term regulation of appetite and body weight

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Role of endogenous ghrelin in the hyperphagia of mice with streptozotocin-induced diabetes.

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Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice

21 January 2018

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Subcutaneous ghrelin enhances acute food intake in malnourished patients who receive maintenance peritoneal dialysis: a randomized, placebo-controlled trial

21 January 2018

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Ghrelin enhances gastric emptying in diabetic gastroparesis: a double blind, placebo controlled, crossover study.

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Growth hormone secretagogue (ghrelin-) receptors--a complex drug target for the regulation of body weight

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Rapid rewiring of arcuate nucleus feeding circuits by leptin.

21 January 2018

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Ghrelin controls hippocampal spine synapse density and memory performance

21 January 2018

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Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake

21 January 2018

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Lack of interaction between peripheral injection of CCK and obestatin in the regulation of gastric satiety signaling in rodents

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Effects of obestatin on energy balance and growth hormone secretion in rodents.

21 January 2018

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Gut hormone PYY(3-36) physiologically inhibits food intake

21 January 2018

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Peptide YY3-36 inhibits food intake in mice through a melanocortin-4 receptor-independent mechanism.

21 January 2018

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The importance of acclimatisation and habituation to experimental conditions when investigating the anorectic effects of gastrointestinal hormones in the rat.

21 January 2018

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Effects of peptide YY[3-36] on short-term food intake in mice are not affected by prevailing plasma ghrelin levels

21 January 2018

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Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36).

21 January 2018

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Intravenous infusion of peptide YY(3-36) potently inhibits food intake in rats

21 January 2018

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Peptide YY(3-36) inhibits gastric emptying and produces acute reductions in food intake in rhesus monkeys.

21 January 2018

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Blockade of the neuropeptide Y Y2 receptor with the specific antagonist BIIE0246 attenuates the effect of endogenous and exogenous peptide YY(3-36) on food intake

21 January 2018

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Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity

21 January 2018

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Critical role for peptide YY in protein-mediated satiation and body-weight regulation

21 January 2018

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Inhibition of food intake in obese subjects by peptide YY3-36

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE05484

Effects of Roux-en-Y gastric bypass surgery on fasting and postprandial concentrations of plasma ghrelin, peptide YY, and insulin

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE05484

Attenuated peptide YY release in obese subjects is associated with reduced satiety.

21 January 2018

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Peptide YY is secreted after oral glucose administration in a gender-specific manner

21 January 2018

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Ghrelin, peptide YY, glucose-dependent insulinotropic polypeptide, and hunger responses to a mixed meal in anorexic, obese, and control female adolescents

21 January 2018

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Effect of peptide YY3-36 on food intake in humans

21 January 2018

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Intravenous peptide YY3-36 and Y2 receptor antagonism in the rat: effects on feeding behaviour.

21 January 2018

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Actions of CCK in the controls of food intake and body weight: lessons from the CCK-A receptor deficient OLETF rat.

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Cholecystokinin and satiety: current perspectives

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Untangling the effects of hunger, anxiety, and nausea on energy intake during intravenous cholecystokinin octapeptide (CCK-8) infusion.

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The biology of incretin hormones

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Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double-blind, randomized, controlled trial

21 January 2018

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Roles of pancreatic polypeptide in regulation of food intake

21 January 2018

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Pancreatic polypeptide reduces appetite and food intake in humans

21 January 2018

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Characterization of the effects of pancreatic polypeptide in the regulation of energy balance

21 January 2018

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A role for pancreatic polypeptide in the regulation of gastric emptying and short-term metabolic control

21 January 2018

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A randomized study and open-label extension evaluating the long-term efficacy of pramlintide as an adjunct to insulin therapy in type 1 diabetes

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Inhibition of gastric inhibitory polypeptide signaling prevents obesity

21 January 2018

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21 January 2018

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Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes

21 January 2018

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Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes

21 January 2018

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Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea

21 January 2018

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Biologic actions and therapeutic potential of the proglucagon-derived peptides

21 January 2018

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Peripheral oxyntomodulin reduces food intake and body weight gain in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Repeated ICV administration of oxyntomodulin causes a greater reduction in body weight gain than in pair-fed rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: a randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Peptide YY(3-36) inhibits both anorexigenic proopiomelanocortin and orexigenic neuropeptide Y neurons: implications for hypothalamic regulation of energy homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Anatomy and regulation of the central melanocortin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Neuropeptide Y and peptide YY inhibit excitatory synaptic transmission in the rat dorsal motor nucleus of the vagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

The role of the vagal nerve in peripheral PYY3-36-induced feeding reduction in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

The effect of SMS 201-995 on meal and CCK-stimulated peptide YY release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

The influence of insulin on circulating ghrelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Circulating ghrelin concentrations are lowered by intracerebroventricular insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Glucagon suppression of ghrelin secretion is exerted at hypothalamus-pituitary level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Peptide YY3-36 and glucagon-like peptide-17-36 inhibit food intake additively.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Gut hormones in inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Peptide YY levels are elevated after gastric bypass surgery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Gut hormone profiles following bariatric surgery favor an anorectic state, facilitate weight loss, and improve metabolic parameters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Does gut hormone PYY3–36 decrease food intake in rodents?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Rapid development of tolerance to the behavioural actions of cholecystokinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

Ghrelin increases energy intake in cancer patients with impaired appetite: acute, randomized, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Enhancement of feeding suppression by PYY(3-36) in rats with area postrema ablations

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Effects of PYY[3-36] in rodent models of diabetes and obesity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Peripheral administration of PYY(3-36) produces conditioned taste aversion in mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Daily, intermittent intravenous infusion of peptide YY(3-36) reduces daily food intake and adiposity in rats

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Infusion of cholecystokinin between meals into free-feeding rats fails to prolong the intermeal interval

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Oxyntomodulin suppresses appetite and reduces food intake in humans

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Oxyntomodulin inhibits food intake in the rat

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Pre-obese and obese agouti mice are sensitive to the anorectic effects of peptide YY(3-36) but resistant to ghrelin

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Ghrelin does not stimulate food intake in patients with surgical procedures involving vagotomy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Gut hormones in tropical malabsorption

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Peptide YY abnormalities in gastrointestinal diseases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021

Effect of partial ileal bypass on the gut hormone responses to food in man

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05484

7 January 2021