A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis (Q28280037)

GOA release 2020-03-11

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12

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George A. Garinis

George A Garinis

2

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Arjan F Theil

11

Arjan F Theil

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Jan Hoeijmakers

18

Jan H J Hoeijmakers

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Jan Vijg

16

Jan Vijg

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author name string

Laura J Niedernhofer

1

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Anja Raams

3

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Astrid S Lalai

4

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Andria Rasile Robinson

5

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Esther Appeldoorn

6

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Hanny Odijk

7

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Roos Oostendorp

8

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Anwaar Ahmad

9

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Wibeke van Leeuwen

10

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Gijsbertus T J van der Horst

13

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Peter Meinecke

14

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Wim J Kleijer

15

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Nicolaas G J Jaspers

Regulation and function of insulin-like growth factor-binding protein-1.

17

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language of work or name

English

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publication date

21 December 2006

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published in

Nature

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volume

444

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issue

7122

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page(s)

1038-43

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cites work

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Activity and mRNA levels of enzymes involved in hepatic fatty acid synthesis and oxidation in mice fed conjugated linoleic acid

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Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice

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Aging and genome maintenance: lessons from the mouse?

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What can progeroid syndromes tell us about human aging?

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Accelerating aging by mouse reverse genetics: a rational approach to understanding longevity

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Evaluating evidence for aging

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Understanding the odd science of aging

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The plasticity of aging: insights from long-lived mutants

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Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging

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Divide and conquer: nucleotide excision repair battles cancer and ageing

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Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease

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The active site of the DNA repair endonuclease XPF-ERCC1 forms a highly conserved nuclease motif

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Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1

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The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks

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Characterization of molecular defects in xeroderma pigmentosum group F in relation to its clinically mild symptoms

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Homozygous R788W point mutation in the XPF gene of a patient with xeroderma pigmentosum and late-onset neurologic disease

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7 January 2021

Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning

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7 January 2021

Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence

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7 January 2021

Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF

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7 January 2021

Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA.

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7 January 2021

Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice

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7 January 2021

New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen

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A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan.

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Gene expression profile of aging and its retardation by caloric restriction

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Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice

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Hepatic polyploidy and liver growth control.

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Aging, tumor suppression and cancer: high wire-act!

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Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span

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Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

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Modulation of mammalian life span by the short isoform of p53.

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Cellular senescence in aging primates.

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DNA modifications by the mutagen glyoxal: adduction to G and C, deamination of C and GC and GA cross-linking.

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Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells

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Assessment of cisplatin-induced nephrotoxicity by microarray technology

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Induction of hepatic insulin-like growth factor binding protein-1 (IGFBP-1) in rats by dietary n-6 polyunsaturated fatty acids.

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ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes

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DNA repair, genome stability, and aging

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Possible acceleration of aging by adjuvant chemotherapy: a cause of early onset frailty?

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7 January 2021

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

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7 January 2021

Rapid and reversible induction of the longevity, anticancer and genomic effects of caloric restriction

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7 January 2021

Caloric restriction, hormesis and life history plasticity

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7 January 2021

Neuroendocrine control of growth hormone secretion

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Mutations that increase the life span of C. elegans inhibit tumor growth.

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Identifiers

DOI

10.1038/NATURE05456

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1925729

1009966777

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Fatcat ID

release_7u5e6p2a5fa3jmwj5dofghfzrm

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Fatcat

https://api.fatcat.wiki/v0/release/7u5e6p2a5fa3jmwj5dofghfzrm

24 November 2022

mapped directly with Wikidata item

1925729

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference