Host-reactive CD8+ memory stem cells in graft-versus-host disease (Q28281894)

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Gerard Joe

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Jiang Zhu

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Stephen G Emerson

Arrested differentiation, the self-renewing memory lymphocyte, and vaccination.

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language of work or name

English

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publication date

December 2005

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published in

Nature Medicine

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volume

11

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issue

12

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page(s)

1299-305

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cites work

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Progressive differentiation and selection of the fittest in the immune response

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Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus In vivo

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Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

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Skewed maturation of memory HIV-specific CD8 T lymphocytes

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Molecular and functional profiling of memory CD8 T cell differentiation.

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Quiescent phenotype of tumor-specific CD8+ T cells following immunization

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Antigen-independent memory CD8 T cells do not develop during chronic viral infection

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Phenotypic and functional characterisation of CCR7+ and CCR7- CD4+ memory T cells homing to the joints in juvenile idiopathic arthritis

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Recent advances in graft-versus-host disease (GVHD) prevention

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Acute graft-vs-host disease: pathobiology and management

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The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation

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The Pathophysiology of Acute Graft-versus-Host Disease

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Chronic graft versus host disease

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Effector and memory T-cell differentiation: implications for vaccine development

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Severe chronic graft-versus-host disease is characterized by a preponderance of CD4(+) effector memory cells relative to central memory cells.

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T cell death and memory

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Lineage relationship and protective immunity of memory CD8 T cell subsets

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Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes

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Modelling T-cell memory by genetic marking of memory T cells in vivo

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Priming of memory but not effector CD8 T cells by a killed bacterial vaccine

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Linear differentiation of cytotoxic effectors into memory T lymphocytes

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Dendritic cell-activated CD44hiCD8+ T cells are defective in mediating acute graft-versus-host disease but retain graft-versus-leukemia activity.

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Reconstructing immunity after allogeneic transplantation

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Human CD62L- memory T cells are less responsive to alloantigen stimulation than CD62L+ naive T cells: potential for adoptive immunotherapy and allodepletion.

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Transfer of allogeneic CD62L- memory T cells without graft-versus-host disease

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Alloreactive memory T cells are responsible for the persistence of graft-versus-host disease.

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Immunohistochemical study of skin lesions in acute and chronic graft versus host disease following bone marrow transplantation

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Out of Eden: stem cells and their niches

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Preterminal host dendritic cells in irradiated mice prime CD8+ T cell-mediated acute graft-versus-host disease

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Turnover of memory-phenotype CD8+ T cells

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IL-15 is a growth factor and an activator of CD8 memory T cells

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Memory CD8 T-cell differentiation during viral infection

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Interleukin-15 and the regulation of lymphoid homeostasis.

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Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells

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IL-15 Promotes the Survival of Naive and Memory Phenotype CD8+ T Cells

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Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells

21 January 2018

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Host dendritic cells alone are sufficient to initiate acute graft-versus-host disease

21 January 2018

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Differential In Vivo Persistence of Two Subsets of Memory Phenotype CD8 T Cells Defined by CD44 and CD122 Expression Levels

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Maintaining the norm: T-cell homeostasis

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7 January 2021

Immunohistochemical analysis of T cell phenotypes in patients with graft-versus-host disease following allogeneic bone marrow transplantation.

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7 January 2021

Donor-derived IL-15 is critical for acute allogeneic graft-versus-host disease

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7 January 2021

Prevention of graft versus host disease by inactivation of host antigen-presenting cells

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7 January 2021

Donor APCs are required for maximal GVHD but not for GVL

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7 January 2021

Long-term T cell fitness and proliferation is driven by AMPK-dependent regulation of reactive oxygen species

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7 January 2021