Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction (Q28287126)

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25 December 2019

title

Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction (English)

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25 December 2019

1

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7

Koji Eto

1 reference

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2

Hideo Ema

1 reference

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author name string

Jun Ooehara

3

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Satoshi Yamazaki

4

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25 December 2019

Yuko Tadokoro

5

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25 December 2019

Akiko Yamasaki

6

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25 December 2019

Satoshi Takaki

8

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25 December 2019

Kiyoshi Takatsu

9

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Hiromitsu Nakauchi

10

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language of work or name

English

0 references

publication date

6 February 2007

1 reference

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number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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volume

104

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issue

7

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page(s)

2349-2354

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describes a project that uses

25 December 2019

ImageJ

1 reference

11 June 2022

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inferred from PubMed Central ID database lookup

cites work

Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways

1 reference

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Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk

20 March 2017

1 reference

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Characterization of Lnk. An adaptor protein expressed in lymphocytes

20 March 2017

1 reference

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Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores

20 March 2017

1 reference

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Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK.

22 April 2017

1 reference

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Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

29 September 2017

1 reference

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Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis

29 September 2017

1 reference

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Asymmetric division and lineage commitment at the level of hematopoietic stem cells: inference from differentiation in daughter cell and granddaughter cell pairs

29 September 2017

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Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice

29 September 2017

1 reference

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Drug synergism: its detection and applications

29 September 2017

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Quantitative assessment of the stem cell self-renewal capacity.

29 September 2017

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Control of B cell production by the adaptor protein lnk. Definition Of a conserved family of signal-modulating proteins

29 September 2017

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Introduction to stem cell biology in vitro. Threshold to the future.

29 September 2017

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Isobolographic analysis of interactions: an update on applications and utility

29 September 2017

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Differentiation and proliferation of hematopoietic stem cells

29 September 2017

1 reference

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Primitive hemopoietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations.

29 September 2017

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Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells

29 September 2017

1 reference

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Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk.

2 June 2018

1 reference

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Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry

2 June 2018

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Forkhead transcription factors contribute to execution of the mitotic programme in mammals

2 June 2018

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In vitro self-renewal division of hematopoietic stem cells

2 June 2018

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Age-associated characteristics of murine hematopoietic stem cells

2 June 2018

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Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/Wv mice.

2 June 2018

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Life span of multipotential hematopoietic stem cells in vivo

2 June 2018

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2 June 2018

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Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events

21 January 2018

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Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis

21 January 2018

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Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway.

21 January 2018

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Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice

21 January 2018

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12 December 2020

Characterization of the murine immunological signaling network with phosphospecific flow cytometry

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12 December 2020

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

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12 December 2020

Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0606238104

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17284614%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

ADS bibcode

2007PNAS..104.2349S

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17284614%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

2 references