Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity (Q28287290)

Marco van Eijk

5

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Tom Wennekes

Tom Wennekes

10

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Jaswinder K. Sethi

Jaswinder K Sethi

11

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Stephen O'Rahilly

Stephen O'Rahilly

12

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Johannes Aerts

Johannes M Aerts

1

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Mireille J Serlie

9

Mireille J Serlie

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author name string

Roelof Ottenhoff

2

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Andrew S Powlson

3

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Aldo Grefhorst

4

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Peter F Dubbelhuis

6

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Jan Aten

7

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Folkert Kuipers

8

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Hermen S Overkleeft

Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2

13

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language of work or name

English

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publication date

May 2007

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published in

Diabetes

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volume

56

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issue

5

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page(s)

1341-9

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cites work

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Ceramides in insulin resistance and lipotoxicity

29 September 2017

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Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob mice

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29 September 2017

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Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells

29 September 2017

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A turn in the road: How studies on the pharmacology of glucosylceramide synthase inhibitors led to the identification of a lysosomal phospholipase A2 with ceramide transacylase activity

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Combinatorial ganglioside biosynthesis

29 September 2017

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Ganglioside GM3 participates in the pathological conditions of insulin resistance

29 September 2017

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Miglitol: a review of its therapeutic potential in type 2 diabetes mellitus

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TNF-alpha and insulin resistance: summary and future prospects

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Ceramide content is increased in skeletal muscle from obese insulin-resistant humans

29 September 2017

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Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation.

2 June 2018

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Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling

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Inhibitory effect of ceramide on insulin-induced protein kinase Czeta translocation in rat adipocytes

27 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/17287460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Generation of specific deoxynojirimycin-type inhibitors of the non-lysosomal glucosylceramidase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17287460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antihyperglycemic effects of N-containing sugars from Xanthocercis zambesiaca, Morus bombycis, Aglaonema treubii, and Castanospermum australe in streptozotocin-diabetic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17287460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DB06-1619

1 reference

3481072

3481072

1 reference

1 reference

1 reference