Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases (Q28289727)

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O Truong

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D R Katz

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M D Waterfield

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P M Brickell

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I Gout

Modular binding domains in signal transduction proteins

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language of work or name

English

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publication date

1 August 1996

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published in

Current Biology

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volume

6

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issue

8

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page(s)

981-8

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cites work

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Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

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The GTPase dynamin binds to and is activated by a subset of SH3 domains

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Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1

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Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I

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An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane

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Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

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Structure-function relationships in Src family and related protein tyrosine kinases

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The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction

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The B-cell antigen receptor complex: structure and signal transduction

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Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

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Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

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Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

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7 January 2021

WASP gene mutations in Wiskott-Aldrich syndrome and X-linked thrombocytopenia

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Identification of WASP mutations in patients with Wiskott-Aldrich syndrome and isolated thrombocytopenia reveals allelic heterogeneity at the WAS locus

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Identification of mutations in the Wiskott-Aldrich syndrome gene and characterization of a polymorphic dinucleotide repeat at DXS6940, adjacent to the disease gene

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X-linked thrombocytopenia and Wiskott-Aldrich syndrome are allelic diseases with mutations in the WASP gene

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7 January 2021

Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

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T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome

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Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice

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Focal adhesion kinase in the brain: novel subcellular localization and specific regulation by Fyn tyrosine kinase in mutant mice

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Specific and redundant roles of Src and Fyn in organizing the cytoskeleton.

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Evidence for defective transmembrane signaling in B cells from patients with Wiskott-Aldrich syndrome

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Reconstitution of T cell receptor zeta-mediated calcium mobilization in nonlymphoid cells.

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Characterization of p59fyn-mediated signal transduction on T cell activation

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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Accelerated high‐sensitivity microsequencing of proteins and peptides using a miniature reaction cartridge

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Structure and expression of c-fgr protooncogene mRNA in Epstein-Barr virus converted cell lines

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