Cryopyrin activates the inflammasome in response to toxins and ATP (Q28291313)

2

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Kim Newton

3

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Jacqueline McBride

4

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Karen O'Rourke

5

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Meron Roose-Girma

6

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Wyne P Lee

7

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Yvette Weinrauch

8

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Denise M Monack

9

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Vishva M Dixit

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

10

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language of work or name

English

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publication date

9 March 2006

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published in

Nature

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volume

440

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page(s)

228-32

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issue

7081

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cites work

1 reference

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7 January 2021

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

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The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

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PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

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7 January 2021

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

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Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC

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CATERPILLER: a novel gene family important in immunity, cell death, and diseases

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Altered cytokine production in mice lacking P2X(7) receptors

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Interleukin 1 is processed and released during apoptosis

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7 January 2021

ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules

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7 January 2021

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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7 January 2021

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

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Maitotoxin and P2Z/P2X(7) purinergic receptor stimulation activate a common cytolytic pore

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Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

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7 January 2021

Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

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7 January 2021

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

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7 January 2021

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

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7 January 2021

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

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Multiple roles of CLAN (caspase-associated recruitment domain, leucine-rich repeat, and NAIP CIIA HET-E, and TP1-containing protein) in the mammalian innate immune response

1 reference

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7 January 2021

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

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7 January 2021

Genetic clues to understanding periodic fevers, and possible therapies

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Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

1 reference

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7 January 2021

Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis

1 reference

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7 January 2021

Identifiers

DOI

10.1038/NATURE04515

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

342663

1025852033

0 references

Fatcat ID

release_m5ykhg745rf2jjfqbf73yn5o5u

0 references

342663

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference