The role of Tec protein-tyrosine kinase in T cell signaling (Q28292757)

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M Ghiotto

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B Barbarat

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D Olive

Journal of Biological Chemistry

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language of work or name

English

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publication date

8 January 1999

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published in

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volume

274

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issue

2

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page(s)

607-17

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cites work

Protein tyrosine kinases in the initiation of antigen receptor signaling

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Tec homology (TH) adjacent to the PH domain.

21 January 2018

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Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase

21 January 2018

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A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

21 January 2018

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Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain

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Regulatory intramolecular association in a tyrosine kinase of the Tec family

21 January 2018

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Identification of Itk/Tsk Src homology 3 domain ligands

21 January 2018

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Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction

21 January 2018

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Tec kinase associates with c-kit and is tyrosine phosphorylated and activated following stem cell factor binding

21 January 2018

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Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases

21 January 2018

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Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases

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The Btk subfamily of cytoplasmic tyrosine kinases: structure, regulation and function

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itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2

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Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk

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A novel human tyrosine kinase gene inducible in T cells by interleukin 2

21 January 2018

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CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

21 January 2018

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CD2 signaling in T cells involves tyrosine phosphorylation and activation of the Tec family kinase, EMT/ITK/TSK.

21 January 2018

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Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk.

21 January 2018

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SOCS-1/JAB/SSI-1 can bind to and suppress Tec protein-tyrosine kinase

21 January 2018

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Antibody and B7/BB1-mediated ligation of the CD28 receptor induces tyrosine phosphorylation in human T cells

21 January 2018

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Signal transduction by CD28 costimulatory receptor on T cells. B7-1 and B7-2 regulation of tyrosine kinase adaptor molecules

21 January 2018

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Itk negatively regulates induction of T cell proliferation by CD28 costimulation

21 January 2018

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Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase association

21 January 2018

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The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras

21 January 2018

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CD28 mAbs with distinct binding properties differ in their ability to induce T cell activation: analysis of early and late activation events

21 January 2018

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Functional LCK Is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ITK.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.2.607

T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Structural basis for the binding of proline-rich peptides to SH3 domains

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.2.607

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Functional role of GTPase-activating protein in cell transformation by pp60v-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Activation of src family kinase lck following CD28 crosslinking in the Jurkat leukemic cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Both T cell receptor (TcR)-CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR-CD3-independent and CD45-dependent activation of p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Src family protein tyrosine kinases induce autoactivation of Bruton's tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Regulation of Btk by Src family tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Regulation of Btk function by a major autophosphorylation site within the SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

PI 3-kinase: a pivotal pathway in T-cell activation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Constitutive membrane association potentiates activation of Bruton tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

Tyrosine phosphorylation and association with phospholipase C gamma-1 of the GAP-associated 62-kD protein after CD2 stimulation of Jurkat T cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607

A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.2.607