The presenilin genes: a new gene family involved in Alzheimer disease pathology (Q28293835)

Christine Van Broeckhoven

Europe PubMed Central

title

The presenilin genes: a new gene family involved in Alzheimer disease pathology (English)

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object named as

Christine Van Broeckhoven

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author name string

M Cruts

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L Hendriks

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C Van Broeckhoven

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Marc Cruts

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Lydia Hendriks

Molecular genetics of Alzheimer disease: identification of genes and gene mutations

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language of work or name

English

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publication date

1996

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September 1996

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published in

Human Molecular Genetics

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volume

5 Spec No

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5

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issue

Supplement_1

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page(s)

1449-55

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1449-1455

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cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

A beta A4 amyloid precursor protein gene and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Alzheimer's disease: the amyloid cascade hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Mapping of a gene predisposing to early-onset Alzheimer's disease to chromosome 14q24.3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal to the alpha 1-antichymotrypsin gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Genetic and physical characterization of the early-onset Alzheimer's disease AD3 locus on chromosome 14q24.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

A yeast artificial chromosome contig from human chromosome 14q24 spanning the Alzheimer's disease locus AD3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

The c-fos gene and early-onset familial Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Analysis of the c-FOS gene on chromosome 14 and the promoter of the amyloid precursor protein gene in familial Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Genetic analysis of the cellular oncogene fos in patients with chromosome 14 encoded Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Mutation analysis of the chromosome 14q24.3 dihydrolipoyl succinyltransferase (DLST) gene in patients with early-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Familial Alzheimer's disease in American descendants of the Volga Germans: probable genetic founder effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

A familial Alzheimer's disease locus on chromosome 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Genomic structure and expression of STM2, the chromosome 1 familial Alzheimer disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Identification and characterization of presenilin I-467, I-463 and I-374.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Mutations of the presenilin I gene in families with early-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Presenilins and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Missense mutations of the PS-1/S182 gene in German early-onset Alzheimer's disease patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Mutation analysis of presenillin 1 gene in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

APOE genotype does not modulate age of onset in families with chromosome 14 encoded Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Genetic association between intronic polymorphism in presenilin-1 gene and late-onset Alzheimer's disease. Alzheimer's Disease Collaborative Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Presenilin-1 polymorphism and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Apolipoprotein E genotypes and age of onset in early-onset familial Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Regional and cellular presenilin 1 gene expression in human and rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

S182 protein in Alzheimer's disease neuritic plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Beta APP mRNA transcription is increased in cultured fibroblasts from the familial Alzheimer's disease-1 family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Three different mutations of presenilin 1 gene in early-onset Alzheimer's disease families

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449

Incomplete penetrance of familial Alzheimer's disease in a pedigree with a novel presenilin-1 gene mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F5.SUPPLEMENT_1.1449