CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity (Q28294122)

25

Massimo Loda

0 references

Matthew Meyerson

27

Matthew Meyerson

0 references

Josep Tabernero Caturla

22

Josep Tabernero

0 references

Jordi Barretina Ginesta

19

Jordi Barretina

0 references

Craig H Mermel

18

Craig Mermel

0 references

Charles S. Fuchs

24

Charles S Fuchs

0 references

Pablo Tamayo

12

Pablo Tamayo

0 references

William C Hahn

28

William C Hahn

0 references

David E Root

23

David E Root

0 references

Jesse S Boehm

15

Jesse S Boehm

0 references

Shuji Ogino

10

Shuji Ogino

0 references

Stephen P. Finn

13

Stephen Finn

0 references

Isil Guney

6

Isil Guney

0 references

Yashaswi Shrestha

14

Yashaswi Shrestha

0 references

Ramesh Shivdasani

26

Ramesh A Shivdasani

0 references

author name string

Ron Firestein

1

0 references

Adam J Bass

2

0 references

So Young Kim

3

0 references

Ian F Dunn

4

0 references

Serena J Silver

5

0 references

Ellen Freed

7

0 references

Azra H Ligon

8

0 references

Natalie Vena

9

0 references

Milan G Chheda

11

0 references

Supriya Jain

16

0 references

Emeric Bojarski

17

0 references

Jennifer A Chan

Characterizing the cancer genome in lung adenocarcinoma

20

0 references

language of work or name

English

0 references

publication date

25 September 2008

0 references

published in

Nature

0 references

volume

455

0 references

page(s)

547-51

0 references

issue

7212

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Identification of c-MYC as a target of the APC pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Genetic alterations during colorectal-tumor development

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Myc deletion rescues Apc deficiency in the small intestine

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Linking colorectal cancer to Wnt signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8

9 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

The mammalian Mediator complex and its role in transcriptional regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Targeting of CDK8 to a promoter-proximal RNA element demonstrates catalysis-dependent activation of gene expression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Beta-catenin mutations in cell lines established from human colorectal cancers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Automated subcellular localization and quantification of protein expression in tissue microarrays.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587138

Relationship of gene expression and chromosomal abnormalities in colorectal cancer

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18794900

12 December 2020

inferred from PubMed ID database lookup

Constitutive activation of Wnt/beta-catenin signaling pathway in migration-active melanoma cells: role of LEF-1 in melanoma with increased metastatic potential

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18794900

12 December 2020

inferred from PubMed ID database lookup

Integrative genomic approaches identify IKBKE as a breast cancer oncogene

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE07179

7 January 2021

inferred from DOI database lookup

Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE07179

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE07179

1 reference

Dimensions Publication ID

650422

1010877750

0 references

650422

1 reference

1 reference

1 reference