Absence of alpha 7 integrin in dystrophin-deficient mice causes a myopathy similar to Duchenne muscular dystrophy (Q28297222)

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Michael Willem

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Alexander Werner

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Gennadij Raivich

4

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Michael Emerson

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Ludwig Neyses

Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

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language of work or name

English

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publication date

15 March 2006

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published in

Human Molecular Genetics

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volume

15

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page(s)

989-98

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issue

6

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cites work

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Dystrophin: the protein product of the Duchenne muscular dystrophy locus

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Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix

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A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin.

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Three muscular dystrophies: loss of cytoskeleton-extracellular matrix linkage.

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Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models.

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Pulmonary manifestations of neuromuscular disease with special reference to Duchenne muscular dystrophy and spinal muscular atrophy

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The heart in human dystrophinopathies

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X chromosome-linked muscular dystrophy (mdx) in the mouse

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Integrins: bidirectional, allosteric signaling machines

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Integrins: redundant or important players in skeletal muscle?

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Absence of integrin alpha 7 causes a novel form of muscular dystrophy

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Mutations in the integrin alpha7 gene cause congenital myopathy

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Animal models for muscular dystrophy show different patterns of sarcolemmal disruption.

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Integrins (alpha7beta1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophy

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Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice

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Transgenic expression of {alpha}7{beta}1 integrin maintains muscle integrity, increases regenerative capacity, promotes hypertrophy, and reduces cardiomyopathy in dystrophic mice

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Immunolocalization and developmental expression of dystrophin related protein in skeletal muscle.

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A- and B-utrophin have different expression patterns and are differentially up-regulated in mdx muscle

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Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle

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Increased calcium influx in dystrophic muscle

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The pulmonary manifestations of left heart failure.

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Fast-twitch skeletal muscles of dystrophic mouse pups are resistant to injury from acute mechanical stress

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Structural and functional analysis of the recombinant G domain of the laminin alpha4 chain and its proteolytic processing in tissues

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Genetic compensation for sarcoglycan loss by integrin alpha7beta1 in muscle

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Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy

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Defective myoblasts identified in Duchenne muscular dystrophy

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Duchenne/Becker muscular dystrophy: a short overview of the gene, the protein, and current diagnostics

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Fiber regeneration is not persistent in dystrophic (MDX) mouse skeletal muscle

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Myogenic stem cell function is impaired in mice lacking the forkhead/winged helix protein MNF

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Disruption of DAG1 in differentiated skeletal muscle reveals a role for dystroglycan in muscle regeneration.

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Regulation of alpha7 integrin by mechanical stress during skeletal muscle regeneration

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Expression of alpha7beta1 integrin splicing variants during skeletal muscle regeneration.

21 January 2018

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Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins

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The mdx-amplification-resistant mutation system assay, a simple and rapid polymerase chain reaction-based detection of the mdx allele

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Disruption of the sarcoglycan-sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy

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Defective integrin switch and matrix composition at alpha 7-deficient myotendinous junctions precede the onset of muscular dystrophy in mice.

21 January 2018

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Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach

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Different dystrophin-like complexes are expressed in neurons and glia

21 January 2018

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Dissociation of the dystroglycan complex in caveolin-3-deficient limb girdle muscular dystrophy

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The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy

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