Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons (Q28298056)

1

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Diane B Re

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Tetsuya Nagata

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Alcmène Chalazonitis

4

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Thomas M Jessell

5

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Hynek Wichterle

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

6

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language of work or name

English

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publication date

May 2007

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published in

Nature Neuroscience

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volume

10

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page(s)

615-22

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issue

5

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cites work

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

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Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

20 March 2017

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Directed differentiation of embryonic stem cells into motor neurons

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Onset and progression in inherited ALS determined by motor neurons and microglia

7 April 2017

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Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

7 April 2017

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Informatics-assisted protein profiling in a transgenic mouse model of amyotrophic lateral sclerosis.

29 September 2017

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Interactions between beta-neuregulin and neurotrophins in motor neuron apoptosis

29 September 2017

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Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

29 September 2017

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Functional properties of motoneurons derived from mouse embryonic stem cells.

29 September 2017

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Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

29 September 2017

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ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

29 September 2017

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Increased superoxide dismutase activity improves survival of cultured postnatal midbrain neurons.

2 June 2018

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Transforming growth factor alpha, but not epidermal growth factor, promotes the survival of sensory neurons in vitro

2 June 2018

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Aging of chick embryo fibroblasts in vitro. III. Polyploid cell accumulation

2 June 2018

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Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport.

2 June 2018

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Voltage-dependent sodium channels in spinal cord motor neurons display rapid recovery from fast inactivation in a mouse model of amyotrophic lateral sclerosis.

27 November 2018

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Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

27 November 2018

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Increased persistent Na(+) current and its effect on excitability in motoneurones cultured from mutant SOD1 mice.

27 November 2018

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alpha-synuclein is required for the fibrillar nature of ubiquitinated inclusions induced by proteasomal inhibition in primary neurons.

27 November 2018

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Functional network integration of embryonic stem cell-derived astrocytes in hippocampal slice cultures.

27 November 2018

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Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

27 November 2018

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Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70.

27 November 2018

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Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

27 November 2018

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A novel and rapid method for culturing pure rat spinal cord astrocytes on untreated glass.

27 November 2018

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Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1.

27 November 2018

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Preferential cholinergic projections by embryonic spinal cord neurons within cocultured mouse superior cervical ganglia

27 November 2018

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Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration

27 November 2018

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12 December 2020

Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease

1 reference

12 December 2020

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

12 December 2020

Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Fractin immunostaining for the detection of apoptotic cells and apoptotic bodies in formalin-fixed and paraffin-embedded tissue

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12 December 2020

Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA

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12 December 2020

Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS

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12 December 2020

Identifiers

DOI

10.1038/NN1876

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Dimensions Publication ID

1114733

1026670759

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1114733

1 reference

1 reference

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