Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome (Q28300603)

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A Savelsbergh

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V I Katunin

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W Wintermeyer

Ribosomal translocation: facts and models

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language of work or name

English

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publication date

2 January 1997

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published in

Nature

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volume

385

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issue

6611

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page(s)

37-41

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cites work

1 reference

7 January 2021

Intermediate states in the movement of transfer RNA in the ribosome

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7 January 2021

tRNA topography during translocation: steady-state and kinetic fluorescence energy-transfer studies.

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Testing the classical two-tRNA-site model for the ribosomal elongation cycle

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Mechanism of ribosomal translocation. tRNA binds transiently to an exit site before leaving the ribosome during translocation.

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7 January 2021

The "allosteric three-site model" of elongation cannot be confirmed in a well-defined ribosome system from Escherichia coli

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7 January 2021

Translocation in ribosomes by attachment-detachment of elongation factor G without GTP cleavage: Evidence from a column-bound ribosome system

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7 January 2021

Ribosomal translocation promoted by guanylylimido diphosphate and guanylyl-methylene diphosphonate

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7 January 2021

A complex profile of protein elongation: translating chemical energy into molecular movement

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7 January 2021

The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution

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7 January 2021

The structure of elongation factor G in complex with GDP: conformational flexibility and nucleotide exchange

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7 January 2021

Crystal structure of active elongation factor Tu reveals major domain rearrangements

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7 January 2021

The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation

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7 January 2021

Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog

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7 January 2021

Crystallographic studies of elongation factor G.

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7 January 2021

Molecular mimicry in protein synthesis?

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7 January 2021

In vivo selection of conditional-lethal mutations in the gene encoding elongation factor G of Escherichia coli

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7 January 2021

Reduced ribosomal binding of eukaryotic elongation factor 2 following ADP-ribosylation. Difference in binding selectivity between polyribosomes and reconstituted monoribosomes

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7 January 2021

The histidine residue of codon 715 is essential for function of elongation factor 2

1 reference

7 January 2021

Pre-steady-state kinetics of ribosomal translocation.

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7 January 2021

GTP consumption of elongation factor Tu during translation of heteropolymeric mRNAs

1 reference

7 January 2021

Transient conformational states of aminoacyl-tRNA during ribosome binding catalyzed by elongation factor Tu.

1 reference

7 January 2021

Codon-dependent conformational change of elongation factor Tu preceding GTP hydrolysis on the ribosome.

1 reference

7 January 2021

Initial binding of the elongation factor Tu.GTP.aminoacyl-tRNA complex preceding codon recognition on the ribosome.

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7 January 2021

Truncated elongation factor G lacking the G domain promotes translocation of the 3' end but not of the anticodon domain of peptidyl-tRNA.

1 reference

7 January 2021

The Inhibition of Ribosomal Translocation by Viomycin

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7 January 2021

Biochemical and crystallographic characterization of a complex of c-Ha-ras p21 and caged GTP with flash photolysis

1 reference

7 January 2021

Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA.

1 reference

7 January 2021

Recognition of the highly conserved GTPase center of 23 S ribosomal RNA by ribosomal protein L11 and the antibiotic thiostrepton.

1 reference

7 January 2021

Cooperative assembly of proteins in the ribosomal GTPase centre demonstrated by their interactions with mutant 23S rRNAs.

1 reference

7 January 2021

The role of guanosine 5′-triphosphate in polypeptide chain elongation

1 reference

7 January 2021

Mechanism of ribosomal translocation. Translocation limits the rate of Escherichia coli elongation factor G-promoted GTP hydrolysis

1 reference

7 January 2021

Factor-free ("non-enzymic") and factor-dependent systems of translation of polyuridylic acid by Escherichia coli ribosomes

1 reference

7 January 2021

Equilibrium measurements of the interactions of guanine nucleotides with Escherichia coli elongation factor G and the ribosome

1 reference

7 January 2021

Fusidic acid-resistant mutants define three regions in elongation factor G of Salmonella typhimurium.

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7 January 2021

The dynamic structure of EF-G studied by fusidic acid resistance and internal revertants.

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7 January 2021

A Model of the Functioning Ribosome: Locking and Unlocking of the Ribosome Subparticles

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7 January 2021

Structural dynamic aspects of protein synthesis on ribosomes.

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7 January 2021

Structural dynamics of translating ribosomes

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7 January 2021

Crystal structure of the motor domain of the kinesin-related motor ncd.

1 reference

7 January 2021

Transcription against an applied force

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7 January 2021

DNA helicases: new breeds of translocating motors and molecular pumps

1 reference

7 January 2021