Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF (Q28301573)

Regulation of the beta-globin locus.

GOA release 2020-03-11

author name string

A C Perkins

series ordinal

1

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A H Sharpe

series ordinal

2

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S H Orkin

series ordinal

3

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language of work or name

English

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publication date

25 May 1995

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published in

Nature

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volume

375

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issue

6529

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page(s)

318-22

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cites work

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7 January 2021

Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes

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Fine structure genetic analysis of a beta-globin promoter

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A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†

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Discrimination among potential activators of the beta-globin CACCC element by correlation of binding and transcriptional properties

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Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

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Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter

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Hemoglobin ontogeny during normal mouse fetal development

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Linkage of beta-thalassaemia mutations and beta-globin gene polymorphisms with DNA polymorphisms in human beta-globin gene cluster

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Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells

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New murine globin bands on electrophoresis may not be new globin chains

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