Molecular dissection reveals decreased activity and not dominant negative effect in human OTX2 mutants (Q28306611)

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19 January 2020

title

Molecular dissection reveals decreased activity and not dominant negative effect in human OTX2 mutants (English)

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19 January 2020

4

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19 January 2020

author name string

Gilles Chatelain

series ordinal

1

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19 January 2020

Nicolas Fossat

series ordinal

2

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19 January 2020

Gilbert Brun

series ordinal

3

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19 January 2020

language of work or name

English

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publication date

11 April 2006

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Journal of Molecular Medicine

19 January 2020

published in

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19 January 2020

volume

84

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19 January 2020

issue

7

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19 January 2020

page(s)

604-615

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https://scigraph.springernature.com/pub.10.1007/s00109-006-0048-2

19 January 2020

exact match

0 references

cites work

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Sequence requirements for synthetic peptide-mediated translocation to the nucleus

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Comparison of X-ray and NMR structures for the Antennapedia homeodomain-DNA complex

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Specific DNA recognition and intersite spacing are critical for action of the bicoid morphogen

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RNA polymerase II conducts a symphony of pre-mRNA processing activities

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The minimal transactivation domain of the basic motif-leucine zipper transcription factor NRL interacts with TATA-binding protein

21 January 2018

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12 December 2020

Cooperative dimerization of paired class homeo domains on DNA.

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12 December 2020

Evolutionary conservation of otd/Otx2 transcription factor action: a genome-wide microarray analysis in Drosophila

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OTX2 activates the molecular network underlying retina pigment epithelium differentiation

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Evolution of homeobox genes: Q50 Paired-like genes founded the Paired class

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A sensitive method for the determination of protein-DNA binding specificities

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New Otx2 mRNA isoforms expressed in the mouse brain

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Cooperation of intrinsic and extrinsic signals in the elaboration of regional identity in the posterior cerebral cortex.

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Visceral endoderm mediates forebrain development by suppressing posteriorizing signals

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Functional domains of the cone-rod homeobox (CRX) transcription factor

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The homeobox gene Otx of the jellyfish Podocoryne carnea: role of a head gene in striated muscle and evolution.

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Elements regulating the transcription of human interstitial retinoid-binding protein (IRBP) gene in cultured retinoblastoma cells

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OTX2 regulates expression of DOPAchrome tautomerase in human retinal pigment epithelium

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Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development

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Mouse Otx2 functions in the formation and patterning of rostral head.

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Nuclear trafficking of photoreceptor protein crx: the targeting sequence and pathologic implications

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OTX2 homeoprotein in the developing central nervous system and migratory cells of the olfactory area.

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Alternative usage of Otx2 promoters during mouse development.

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Proteolysis in heat-stressed HeLa cells. Stabilization of ubiquitin correlates with the loss of proline endopeptidase

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A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo

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12 December 2020

A novel nuclear export signal and a REF interaction domain both promote mRNA export by the Epstein-Barr virus EB2 protein.

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12 December 2020

Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor

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12 December 2020

Otx genes are required for tissue specification in the developing eye

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12 December 2020

An indelible lineage marker for Xenopus using a mutated green fluorescent protein.

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12 December 2020

Conservation and diversification in homeodomain-DNA interactions: a comparative genetic analysis

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12 December 2020

Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome

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12 December 2020

Binding properties of the human homeodomain protein OTX2 to a DNA target sequence

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12 December 2020

Specification of the vertebrate eye by a network of eye field transcription factors.

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12 December 2020

Compartment-specific phosphorylation of rat thyroid hormone receptor alpha1 regulates nuclear localization and retention

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12 December 2020

OTX2 directly interacts with LIM1 and HNF-3beta

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12 December 2020

Heterozygous mutations of OTX2 cause severe ocular malformations

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12 December 2020

Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes

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12 December 2020

Regulation of Otx2 expression and its functions in mouse forebrain and midbrain

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12 December 2020

Dissection of a nuclear localization signal

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12 December 2020

Regulated nuclear trafficking of the homeodomain protein otx1 in cortical neurons

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12 December 2020

Cell autonomous and non-cell autonomous functions of Otx2 in patterning the rostral brain.

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12 December 2020

Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm

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12 December 2020