Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis (Q28307739)

1

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Sudipa Saha Roy

2

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Challa Ram Babu

3

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Rajasekhar Dandamudi

4

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Tyler J Curiel

5

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Pablo Vivas-Mejia

6

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Gabriel Lopez-Berestein

7

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Ratna K Vadlamudi

Cyclin-dependent kinase-mediated phosphorylation plays a critical role in the oncogenic functions of PELP1

9

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language of work or name

English

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publication date

15 April 2011

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published in

Clinical Cancer Research

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volume

17

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issue

8

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page(s)

2250-9

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cites work

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Extranuclear functions of ER impact invasive migration and metastasis by breast cancer cells

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PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity

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The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype

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Functional and biological properties of the nuclear receptor coregulator PELP1/MNAR

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Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

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Deregulation of estrogen receptor coactivator proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor in human endometrial tumors

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The transcriptional corepressor, PELP1, recruits HDAC2 and masks histones using two separate domains

20 March 2017

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Potential role of a novel transcriptional coactivator PELP1 in histone H1 displacement in cancer cells

20 March 2017

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Functional interactions between the estrogen receptor coactivator PELP1/MNAR and retinoblastoma protein

20 March 2017

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Molecular cloning and characterization of PELP1, a novel human coregulator of estrogen receptor alpha

20 March 2017

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Ovarian surface epithelium: biology, endocrinology, and pathology

20 March 2017

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AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

20 March 2017

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Nuclear receptor coregulators: cellular and molecular biology

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7 April 2017

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Therapeutic Targeting of ATP7B in Ovarian Carcinoma.

7 April 2017

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The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression

29 September 2017

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Early events in the pathogenesis of epithelial ovarian cancer

29 September 2017

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29 September 2017

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Emerging significance of ER-coregulator PELP1/MNAR in cancer

29 September 2017

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Intraperitoneal delivery of liposomal siRNA for therapy of advanced ovarian cancer

29 September 2017

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Antiangiogenic and antitumor effects of SRC inhibition in ovarian carcinoma

29 September 2017

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Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy.

29 September 2017

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Systemic therapy for ovarian cancer: current status and new treatments

29 September 2017

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Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery

29 September 2017

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Ovarian cancer metastasis: integrating insights from disparate model organisms

29 September 2017

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Orthotopic models are necessary to predict therapy of transplantable tumors in mice

29 September 2017

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29 September 2017

Ovarian cancer biology

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AIB1 polymorphisms predict aggressive ovarian cancer phenotype

29 September 2017

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The role of proteolytic enzymes in the pathology of epithelial ovarian carcinoma.

2 June 2018

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Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts.

2 June 2018

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Role of PELP1/MNAR signaling in ovarian tumorigenesis

2 June 2018

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Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis

27 November 2018

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AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice

27 November 2018

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Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers

27 November 2018

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Combined analysis of p53 and RB pathways in epithelial ovarian cancer.

27 November 2018

1 reference

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The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.

27 November 2018

1 reference

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Expression and antiproliferative effect of a second form of gonadotropin-releasing hormone in normal and neoplastic ovarian surface epithelial cells

27 November 2018

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Evaluation of steroid receptors, coregulators, and molecules associated with uterine receptivity in secretory endometria from untreated women with polycystic ovary syndrome

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