The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels (Q28316466)

1

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T Takagi

2

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D Langosch

3

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J Bormann

4

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H Betz

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

5

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language of work or name

English

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publication date

December 1992

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published in

The EMBO Journal

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volume

11

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issue

12

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page(s)

4305-11

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cites work

1 reference

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The reaction site of a non-competitive antagonist in the delta-subunit of the nicotinic acetylcholine receptor

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High-efficiency transformation of mammalian cells by plasmid DNA

20 March 2017

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Glycine receptor heterogeneity in rat spinal cord during postnatal development

20 March 2017

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Functional chloride channels by mammalian cell expression of rat glycine receptor subunit

20 March 2017

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Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes

20 March 2017

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DNA sequencing with chain-terminating inhibitors

20 March 2017

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Identification and functional expression of a novel ligand binding subunit of the inhibitory glycine receptor

20 March 2017

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Cerebellar GABAA receptor selective for a behavioural alcohol antagonist

20 March 2017

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Alternative splicing generates two isoforms of the alpha 2 subunit of the inhibitory glycine receptor

20 March 2017

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High-expression vectors with multiple cloning sites for construction of trpE fusion genes: pATH vectors

20 March 2017

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The arrangement of the subunits of the acetylcholine receptor of Torpedo californica

7 April 2017

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Convulsant-induced depression of amino acid responses in cultured mouse spinal neurones studied under voltage clamp

29 September 2017

1 reference

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GABA-Benzodiazepine-Barbiturate Receptor Interactions

29 September 2017

1 reference

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Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence

29 September 2017

1 reference

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Monoclonal antibodies and peptide mapping reveal structural similarities between the subunits of the glycine receptor of rat spinal cord.

29 September 2017

1 reference

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Quaternary structure of the acetylcholine receptor

29 September 2017

1 reference

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Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine

29 September 2017

1 reference

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A novel alpha subunit in rat brain GABAA receptors

29 September 2017

1 reference

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The structure of ion channels in membranes of excitable cells

29 September 2017

1 reference

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Functional expression in Xenopus oocytes of the strychnine binding 48 kd subunit of the glycine receptor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

M2 delta, a candidate for the structure lining the ionic channel of the nicotinic cholinergic receptor

29 September 2017

1 reference

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Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Noradrenergic neurons from the locus ceruleus in dissociated cell culture: culture methods, morphology, and electrophysiology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

The inhibitory glycine receptor: a ligand-gated chloride channel of the central nervous system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Cloning and expression of the 58 kd beta subunit of the inhibitory glycine receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Molecular biology of GABAA receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Function and pharmacology of multiple GABAA receptor subunits

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Glycine receptors: heterogeneous and widespread in the mammalian brain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Ligand-gated ion channels in the brain: the amino acid receptor superfamily

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

The noncompetitive blocker [3H]chlorpromazine labels three amino acids of the acetylcholine receptor gamma subunit: implications for the alpha-helical organization of regions MII and for the structure of the ion channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Homology and analogy in transmembrane channel design: lessons from synaptic membrane proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Glutamate receptor channels: novel properties and new clones

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Interaction of barbiturates with dihydropicrotoxinin binding sites related to the GABA receptor-ionophore system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Solubilization of the glycine receptor from rat spinal cord

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Development of sensitivity to GABA and glycine in cultured cerebellar neurons.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Ionic and pharmacological properties of reciprocal inhibition in Xenopus embryo motoneurones.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Photoaffinity labeling of benzodiazepine receptor proteins with the partial inverse agonist [3H]Ro 15-4513: a biochemical and autoradiographic study.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

The glycine receptor deficiency of the mutant mouse spastic: evidence for normal glycine receptor structure and localization.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Purification and characterization of the glycine receptor of pig spinal cord.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

The noncompetitive blocker [(3)H]chlorpromazine labels segment M2 but not segment M1 of the nicotinic acetylcholine receptor alpha-subunit

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Blockade of gamma-aminobutyric acid-gated chloride current in frog sensory neurons by picrotoxin.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

A single amino acid exchange alters the pharmacology of neonatal rat glycine receptor subunit.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Identification of a site in glutamate receptor subunits that controls calcium permeability

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Agonist pharmacology of neonatal and adult glycine receptor alpha subunits: identification of amino acid residues involved in taurine activation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

The 93 kDa protein gephyrin and tubulin associated with the inhibitory glycine receptor are phosphorylated by an endogenous protein kinase

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

On the mechanism of action of picrotoxin on GABA receptor channels in dissociated sympathetic neurones of the rat.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557003

Mapping of antigenic epitopes on the alpha 1 subunit of the inhibitory glycine receptor

27 November 2018

1 reference

12 December 2020

Ion channel formation by synthetic transmembrane segments of the inhibitory glycine receptor — a model study

1 reference

12 December 2020

Localization of the strychnine binding site on the 48-kilodalton subunit of the glycine receptor

1 reference

12 December 2020

The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits

1 reference

12 December 2020

Structural determinants of ion flow through recombinant glutamate receptor channels

1 reference

12 December 2020

UV light-induced cross-linking of strychnine to the glycine receptor of rat spinal cord membranes

1 reference

12 December 2020

Purification by affinity chromatography of the glycine receptor of rat spinal cord

1 reference

12 December 2020

Photoaffinity-labelling of the glycine receptor of rat spinal cord

1 reference

12 December 2020

Primary cultures of mouse spinal cord express the neonatal isoform of the inhibitory glycine receptor

1 reference

12 December 2020

Bicuculline and picrotoxin block gamma-aminobutyric acid-gated Cl- conductance by different mechanisms

1 reference

12 December 2020

Glycine-gated chloride current in acutely isolated rat hypothalamic neurons

1 reference

12 December 2020

Single subunits of the GABAA receptor form ion channels with properties of the native receptor

1 reference

12 December 2020

The Mr 93,000 polypeptide of the postsynaptic glycine receptor complex is a peripheral membrane protein

1 reference

12 December 2020

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: [3H]chlorpromazine labels homologous residues in the beta and delta chains

1 reference

12 December 2020

Artificial reductant enhancement of the Lowry method for protein determination

1 reference

12 December 2020

Modulation by picrotoxin and IPTBO of 3H-flunitrazepam binding to the GABA/benzodiazepine receptor complex of rat cerebellum

1 reference

12 December 2020

Identifiers

426589

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference