Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon (Q28344042)

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English	Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon	scientific article

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5 November 2019

Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon (English)

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5 November 2019

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5 November 2019

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W Markland

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5 November 2019

J Jain

3

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5 November 2019

A D Kwong

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5 November 2019

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1 April 2000

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5 November 2019

Antimicrobial Agents and Chemotherapy

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5 November 2019

44

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5 November 2019

4

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5 November 2019

859-866

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5 November 2019

Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design

1 reference

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20 March 2017

The novel immunosuppressive agent mycophenolate mofetil markedly potentiates the antiherpesvirus activities of acyclovir, ganciclovir, and penciclovir in vitro and in vivo

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20 March 2017

Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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20 March 2017

Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

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29 September 2017

Update on preclinical and clinical experience with mycophenolate mofetil.

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Antiviral agents: characteristic activity spectrum depending on the molecular target with which they interact.

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29 September 2017

The interferon system: a review with emphasis on the role of PKR in growth control

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29 September 2017

Biochemistry and clinical applications of ribavirin

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29 September 2017

Effect of phosphorylated ribavirin on vesicular stomatitis virus transcription

1 reference

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29 September 2017

Mechanism of La Crosse virus inhibition by ribavirin

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29 September 2017

Molecular analysis of the inhibitory effect of phosphorylated ribavirin on the vesicular stomatitis virus in vitro polymerase reaction

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29 September 2017

A three-dimensional model to analyze drug-drug interactions

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29 September 2017

Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the anti-human immunodeficiency virus nucleosides 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=89783

29 September 2017

Inhibition of influenza virus ribonucleic acid polymerase by ribavirin triphosphate

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29 September 2017

The Role ofde novoPurine Synthesis in Lymphocyte Transformation

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29 September 2017

The broad spectrum antiviral agent ribavirin inhibits capping of mRNA

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29 September 2017

Combination therapy of chronic hepatitis C: an important step but not the final goal!

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2 June 2018

A randomized active-controlled trial of mycophenolate mofetil in heart transplant recipients. Mycophenolate Mofetil Investigators.

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2 June 2018

Ribavirin inhibits viral-induced macrophage production of TNF, IL-1, the procoagulant fgl2 prothrombinase and preserves Th1 cytokine production but inhibits Th2 cytokine response.

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Rediscovering mycophenolic acid: a review of its mechanism, side effects, and potential uses

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Effect of ribavirin triphosphate on primer generation and elongation during influenza virus transcription in vitro

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12 December 2020

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10.1128/AAC.44.4.859-866.2000

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5 November 2019

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5 November 2019

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5 November 2019

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