Murine cytomegalovirus stimulates cellular thymidylate synthase gene expression in quiescent cells and requires the enzyme for replication (Q28344246)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10799571%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Murine cytomegalovirus stimulates cellular thymidylate synthase gene expression in quiescent cells and requires the enzyme for replication (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10799571%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

0 references

1

1 reference

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6 November 2019

Ludovica Riera

2

1 reference

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6 November 2019

David Lembo

3

1 reference

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6 November 2019

Marco De Andrea

4

1 reference

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6 November 2019

Marisa Gariglio

5

1 reference

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6 November 2019

author name string

T L Rudge

6

1 reference

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6 November 2019

L F Johnson

7

1 reference

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6 November 2019

S Landolfo

8

1 reference

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6 November 2019

language of work or name

English

0 references

publication date

1 June 2000

1 reference

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6 November 2019

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

Journal of Virology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10799571%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

74

1 reference

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6 November 2019

issue

11

1 reference

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6 November 2019

page(s)

4979-4987

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10799571%20AND%20SRC:MED&resulttype=core&format=json

A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphate

6 November 2019

cites work

1 reference

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Intracellular location of thymidylate synthase and its state of phosphorylation

20 March 2017

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20 March 2017

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Human cytomegalovirus 86-kilodalton IE2 protein blocks cell cycle progression in G(1).

20 March 2017

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29 September 2017

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The cyclin E promoter is activated by human cytomegalovirus 86-kDa immediate early protein

29 September 2017

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New developments in cancer treatment with the novel thymidylate synthase inhibitor raltitrexed ('Tomudex').

29 September 2017

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Cell cycle dysregulation by human cytomegalovirus: influence of the cell cycle phase at the time of infection and effects on cyclin transcription.

29 September 2017

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Identification of a viral kinase that phosphorylates specific E2Fs and pocket proteins

29 September 2017

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Human cytomegalovirus infection results in altered Cdk2 subcellular localization

29 September 2017

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The human cytomegalovirus UL55 (gB) and UL75 (gH) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infection

29 September 2017

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Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates upregulation of the p65 and p105/p50 NF-kappaB promoters

29 September 2017

1 reference

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Human cytomegalovirus infection inhibits G1/S transition.

29 September 2017

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Human cytomegalovirus infection inhibits cell cycle progression at multiple points, including the transition from G1 to S.

29 September 2017

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Analysis of the complete DNA sequence of murine cytomegalovirus

29 September 2017

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Role of folylpolygutamate synthetase (FPGS) in antifolate chemotherapy; a biochemical and clinical update

29 September 2017

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The murine cytomegalovirus immediate-early 1 protein stimulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 promoter

29 September 2017

1 reference

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The human cytomegalovirus IE1-72 protein interacts with the cellular p107 protein and relieves p107-mediated transcriptional repression of an E2F-responsive promoter.

29 September 2017

1 reference

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Human cytomegalovirus inhibits cellular DNA synthesis and arrests productively infected cells in late G1.

29 September 2017

1 reference

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Regulation of mouse thymidylate synthase gene expression in growth-stimulated cells: upstream S phase control elements are indistinguishable from the essential promoter elements

29 September 2017

1 reference

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Splicing signals are required for S-phase regulation of the mouse thymidylate synthase gene

29 September 2017

1 reference

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Lack of an initiator element is responsible for multiple transcriptional initiation sites of the TATA-less mouse thymidylate synthase promoter

29 September 2017

1 reference

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Posttranscriptional regulation of thymidylate synthase gene expression

29 September 2017

1 reference

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CCAAT box-dependent activation of the TATA-less human DNA polymerase alpha promoter by the human cytomegalovirus 72-kilodalton major immediate-early protein

29 September 2017

1 reference

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Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters

29 September 2017

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Interaction of the 72-kilodalton human cytomegalovirus IE1 gene product with E2F1 coincides with E2F-dependent activation of dihydrofolate reductase transcription

29 September 2017

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Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest

29 September 2017

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29 September 2017

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29 September 2017

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Mechanism of selective inhibition of human cytomegalovirus replication by 1-beta-D-arabinofuranosyl-5-fluorouracil

29 September 2017

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The 89,000-Mr murine cytomegalovirus immediate-early protein activates gene transcription

29 September 2017

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The 89,000-Mr murine cytomegalovirus immediate-early protein stimulates c-fos expression and cellular DNA synthesis

29 September 2017

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The mouse thymidylate synthase promoter: essential elements are in close proximity to the transcriptional initiation sites

29 September 2017

1 reference

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Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169.

29 September 2017

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Human cytomegalovirus induces expression of cellular topoisomerase II.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110849

The 5'-flanking region of the mouse thymidylate synthase gene is necessary but not sufficient for normal regulation in growth-stimulated cells

29 September 2017

1 reference

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Transcriptional activation of cellular oncogenes fos, jun, and myc by human cytomegalovirus.

29 September 2017

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A procedure to standardize CAT reporter gene assay

29 September 2017

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E2F mediates dihydrofolate reductase promoter activation and multiprotein complex formation in human cytomegalovirus infection

29 September 2017

1 reference

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Structural organization, expression, and functional characterization of the murine cytomegalovirus immediate-early gene 3

29 September 2017

1 reference

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Stimulation of Ornithine Decarboxylase by Human Cytomegalovirus

29 September 2017

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Biochemical determinants of tumor sensitivity to 5-fluorouracil: Ultrasensitive methods for the determination of 5-fluoro-2′-deoxyuridylate, 2′-deoxyuridylate, and thymidylate synthetase

29 September 2017

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Stimulation of Cellular Thymidine Kinases by Human Cytomegalovirus

29 September 2017

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Murine cytomegalovirus induces expression and enzyme activity of cellular dihydrofolate reductase in quiescent cells

29 September 2017

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Suppression of high mobility group protein T160 expression impairs mouse cytomegalovirus replication

2 June 2018

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Interferon-alpha inhibits the murine cytomegalovirus immediate-early gene expression by down-regulating NF-kappa B activity

2 June 2018

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In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas.

2 June 2018

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Sequence of a cDNA for mouse thymidylate synthase reveals striking similarity with the prokaryotic enzyme

2 June 2018

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Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates

2 June 2018

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Cell cycle phase dependent emergence of thymidylate synthase studied by monoclonal antibody (M-TS-4).

2 June 2018

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ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study

2 June 2018

1 reference

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Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue

2 June 2018

1 reference

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Cellular oncogene activation by human cytomegalovirus Lack of correlation with virus infectivity and immediate early gene expression

2 June 2018

1 reference

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Activation of Proto-Oncogenes: an Immediate Early Event in Human Cytomegalovirus Infection

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110849

Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines

2 June 2018

1 reference

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Folate polyglutamate synthesis and turnover in cultured human fibroblasts

2 June 2018

1 reference

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Folate metabolism in mammalian cells in culture. I Partial characterization of the folate derivatives present in L1210 mouse leukemia cells

2 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10799571

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Localization of the deoxyribonucleotide biosynthetic enzymes ribonucleotide reductase and thymidylate synthase in mouse L cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10799571

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.74.11.4979-4987.2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10799571%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10799571%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference