Cytochrome P-450 2C9 sensitizes human prostate tumor cells to cyclophosphamide via a bystander effect (Q28344743)

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English	Cytochrome P-450 2C9 sensitizes human prostate tumor cells to cyclophosphamide via a bystander effect	scientific article

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scholarly article

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title

Cytochrome P-450 2C9 sensitizes human prostate tumor cells to cyclophosphamide via a bystander effect (English)

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1 reference

D Zhou

1

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Y Lu

series ordinal

2

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M S Steiner

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3

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J T Dalton

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4

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language of work or name

English

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publication date

October 2000

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published in

Antimicrobial Agents and Chemotherapy

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volume

44

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issue

10

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page(s)

2659-63

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Identification of the polymorphically expressed CYP2C19 and the wild-type CYP2C9-ILE359 allele as low-Km catalysts of cyclophosphamide and ifosfamide activation.

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The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

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Interaction of sulfaphenazole derivatives with human liver cytochromes P450 2C: molecular origin of the specific inhibitory effects of sulfaphenazole on CYP 2C9 and consequences for the substrate binding site topology of CYP 2C9

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Induction, inhibition, and some enzymological properties of aryl hydrocarbon hydroxylase in fresh mitogen-activated human lymphocytes

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Identifiers

DOI

10.1128/AAC.44.10.2659-2663.2000

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PMC publication ID

90131

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PubMed publication ID

10991840

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ResearchGate publication ID

12331006

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Cytochrome P-450 2C9 sensitizes human prostate tumor cells to cyclophosphamide via a bystander effect (Q28344743)

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Cytochrome P-450 2C9 sensitizes human prostate tumor cells to cyclophosphamide via a bystander effect (Q28344743)

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