Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins) (Q28345499)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11487529%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins) (English)

1 reference

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10 November 2019

1 reference

1

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10 November 2019

author name string

J Heusinger-Ribeiro

series ordinal

2

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10 November 2019

M Goppelt-Struebe

series ordinal

3

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10 November 2019

language of work or name

English

0 references

publication date

1 August 2001

1 reference

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British Journal of Pharmacology

10 November 2019

published in

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10 November 2019

volume

133

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10 November 2019

issue

7

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10 November 2019

page(s)

1172-1180

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Lysophosphatidic acid receptors

10 November 2019

cites work

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Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells

20 March 2017

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Rho GTPases and signaling networks

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Expression of connective tissue growth factor in human renal fibroblasts: regulatory roles of RhoA and cAMP.

7 April 2017

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Transcriptional regulation of connective tissue growth factor by cortisol in osteoblasts

29 September 2017

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29 September 2017

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The role of lipids in renal disease: future challenges.

29 September 2017

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TGF-beta1 stimulation of fibronectin transcription in cultured human lung fibroblasts requires active geranylgeranyl transferase I, phosphatidylcholine-specific phospholipase C, protein kinase C-delta, and p38, but not erk1/erk2.

29 September 2017

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Current perspectives on statins

29 September 2017

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Specificity, diversity, and regulation in TGF-beta superfamily signaling.

29 September 2017

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The CCN family of angiogenic regulators: the integrin connection

29 September 2017

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Human connective tissue growth factor is expressed in advanced atherosclerotic lesions

29 September 2017

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A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene

29 September 2017

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Transforming growth factor beta induces anchorage-independent growth of NRK fibroblasts via a connective tissue growth factor-dependent signaling pathway.

29 September 2017

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Prevention of progression of renal fibrosis: how far are we?

29 September 2017

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The modular architecture of a new family of growth regulators related to connective tissue growth factor

29 September 2017

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Cell cycle-specific effects of lovastatin

29 September 2017

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Induction of connective tissue growth factor by activation of heptahelical receptors. Modulation by Rho proteins and the actin cytoskeleton

29 September 2017

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The platelet-derived-growth-factor receptor, not the epidermal-growth-factor receptor, is used by lysophosphatidic acid to activate p42/44 mitogen-activated protein kinase and to induce prostaglandin G/H synthase-2 in mesangial cells

2 June 2018

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In vitro effects of simvastatin on tubulointerstitial cells in a human model of cyclosporin nephrotoxicity

2 June 2018

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Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate.

2 June 2018

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Lovastatin modulates in vivo and in vitro the plasminogen activator/plasmin system of rat proximal tubular cells: role of geranylgeranylation and Rho proteins.

2 June 2018

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2 June 2018

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Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts

2 June 2018

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Role of Rho protein in lovastatin-induced breakdown of actin cytoskeleton

2 June 2018

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Inhibition of Ras prenylation: a signaling target for novel anti-cancer drug design

2 June 2018

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Clinical pharmacokinetics of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors

2 June 2018

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Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription.

2 June 2018

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Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0704173

Human mesangial cell production of monocyte chemoattractant protein-1: modulation by lovastatin

21 January 2018

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12 December 2020

Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: down-regulation by cAMP

1 reference

12 December 2020

Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor

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12 December 2020

Inhibition of proliferation of human smooth muscle cells by various HMG-CoA reductase inhibitors; comparison with other human cell types

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12 December 2020

G-protein-mediated signaling in cholesterol-enriched arterial smooth muscle cells. 1. Reduced membrane-associated G-protein content due to diminished isoprenylation of G-gamma subunits and p21ras

1 reference

12 December 2020

Lovastatin-induced inhibition of renal epithelial tubular cell proliferation involves a p21ras activated, AP-1-dependent pathway

1 reference

12 December 2020

Lovastatin reduces glomerular macrophage influx and expression of monocyte chemoattractant protein-1 mRNA in nephrotic rats

1 reference

12 December 2020

Expression of connective tissue growth factor in human renal fibrosis

1 reference

12 December 2020

Connective tissue growth factor: a novel regulator of mucosal repair and fibrosis in inflammatory bowel disease?

1 reference

12 December 2020

Effect of HMG-CoA reductase inhibitors on extracellular matrix expression in human vascular smooth muscle cells

1 reference

12 December 2020

Lovastatin inhibits transforming growth factor-beta1 expression in diabetic rat glomeruli and cultured rat mesangial cells

1 reference

12 December 2020

Low-density lipoprotein-induced expression of interleukin-6, a marker of human mesangial cell inflammation: effects of oxidation and modulation by lovastatin

1 reference

12 December 2020

Connective tissue growth factor expression in the rat remnant kidney model and association with tubular epithelial cells undergoing transdifferentiation

1 reference

12 December 2020

Inhibition of protein isoprenylation impairs rho-regulated early cellular response to genotoxic stress

1 reference

12 December 2020

Defined daily doses in relation to hypolipidaemic efficacy of lovastatin, pravastatin, and simvastatin

1 reference

12 December 2020

Signal transduction pathways responsible for serotonin-mediated prostaglandin G/H synthase expression in rat mesangial cells

1 reference

12 December 2020

Human renal fibroblast cell lines (tFKIF and tNKF) are new tools to investigate pathophysiologic mechanisms of renal interstitial fibrosis

1 reference

12 December 2020

Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0704173

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11487529%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11487529%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference