beta-site APP cleaving enzyme mRNA expression in APP transgenic mice: anatomical overlap with transgene expression and static levels with aging (Q28345657)

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English	beta-site APP cleaving enzyme mRNA expression in APP transgenic mice: anatomical overlap with transgene expression and static levels with aging	scientific article

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3 November 2019

beta-site APP cleaving enzyme mRNA expression in APP transgenic mice: anatomical overlap with transgene expression and static levels with aging (English)

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3 November 2019

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M C Irizarry

1

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3 November 2019

J J Locascio

2

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3 November 2019

B T Hyman

3

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1 January 2001

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3 November 2019

The American Journal of Pathology

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3 November 2019

158

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3 November 2019

1

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3 November 2019

173-177

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3 November 2019

BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein

1 reference

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20 March 2017

Expression analysis of BACE2 in brain and peripheral tissues

1 reference

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20 March 2017

Purification and cloning of amyloid precursor protein beta-secretase from human brain

1 reference

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20 March 2017

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

1 reference

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20 March 2017

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

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20 March 2017

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

1 reference

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20 March 2017

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

1 reference

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6 April 2017

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

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7 April 2017

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

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7 April 2017

Alzheimer disease: mouse models pave the way for therapeutic opportunities

1 reference

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29 September 2017

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

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29 September 2017

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850271

29 September 2017

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

1 reference

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29 September 2017

In situ hybridization analysis of presenilin 1 mRNA in Alzheimer disease and in lesioned rat brain

1 reference

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29 September 2017

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

1 reference

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29 September 2017

Presenilin-1, amyloid precursor protein and amyloid precursor-like protein 2 mRNA levels in human superior frontal cortex during aging.

1 reference

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2 June 2018

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

1 reference

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2 June 2018

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850271

2 June 2018

Developmental regulation of presenilin mRNA expression parallels notch expression.

1 reference

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2 June 2018

Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid beta-peptide deposition in homozygous APP(V717F) transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850271

27 November 2018

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

1 reference

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27 November 2018

Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice.

1 reference

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27 November 2018

Predominance of neuronal mRNAs in individual Alzheimer's disease senile plaques.

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27 November 2018

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850271

27 November 2018

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850271

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Differential regional and cellular distribution of beta-amyloid precursor protein messenger RNAs containing and lacking the Kunitz protease inhibitor domain in the brain of human, rat and mouse.

1 reference

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

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7 January 2021

Identifiers

10.1016/S0002-9440(10)63955-7

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11141490%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11141490%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11141490%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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