Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens (Q28347424)

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P Bozzotti

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C Tougne

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H L Davis

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P H Lambert

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A M Krieg

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C A Siegrist

Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization

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language of work or name

English

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publication date

January 2001

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published in

Immunology

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volume

102

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issue

1

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page(s)

67-76

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cites work

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CpG oligodeoxynucleotides act as adjuvants for pneumococcal polysaccharide-protein conjugate vaccines and enhance antipolysaccharide immunoglobulin G2a (IgG2a) and IgG3 antibodies

20 March 2017

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Bacterial CpG DNA activates immune cells to signal infectious danger.

29 September 2017

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CpG oligodeoxynucleotides rescue BKS-2 immature B cell lymphoma from anti-IgM-mediated growth inhibition by up-regulation of egr-1.

29 September 2017

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CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice

29 September 2017

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CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species.

29 September 2017

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CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity

29 September 2017

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CpG motifs in bacterial DNA trigger direct B-cell activation

29 September 2017

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In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions

29 September 2017

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T cell-independent antigens type 2.

29 September 2017

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T cell regulation of IgG subclass antibody production in response to T-independent antigens

29 September 2017

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The ontogeny of thymic independent antibody responses in vitro in normal mice and mice with an X-linked B cell defect

29 September 2017

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Role of a nonimmunoglobulin cell surface determinant in the activation of B lymphocytes by thymus-independent antigens

29 September 2017

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CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge

29 September 2017

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The consequences of the intracellular retention of pathogen-derived T-cell-independent antigens on protein presentation to T cells.

2 June 2018

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Characterization of the antibody response to type 3 pneumococcal polysaccharide at the cellular level. I. Dose-response studies and the effect of prior immunization on the magnitude of the antibody response.

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Studies on the induction of immunological unresponsiveness to pneumococcal polysaccharide in mice

2 June 2018

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Splenic dependence of the antibody response to thymus-independent (TI-2) antigens

2 June 2018

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Mitogenic synthetic polynucleotides suppress the antibody response to a bacterial polysaccharide

2 June 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01158.X

Neonatal and early life immune responses to various forms of vaccine antigens qualitatively differ from adult responses: predominance of a Th2-biased pattern which persists after adult boosting.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01158.X

Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01158.X

CpG oligodeoxynucleotides overcome the unresponsiveness of neonatal B cells to stimulation with the thymus-independent stimuli anti-IgM and TNP-Ficoll

21 January 2018

1 reference

12 December 2020

Restoration of T cell-independent type 2 induction of Ig secretion by neonatal B cells in vitro

1 reference

12 December 2020

Inhibitory effects of thymus-independent type 2 antigens on MHC class II-restricted antigen presentation: comparative analysis of carbohydrate structures and the antigen presenting cell

1 reference

12 December 2020

CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants

1 reference

12 December 2020

Enhancement of T cell-independent immune responses in vivo by CD40 antibodies

1 reference

12 December 2020

Characterization of early activation events in cord blood B cells after stimulation with T cell-independent activators

1 reference

12 December 2020

CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen

1 reference

12 December 2020

Neonatal murine B lymphocytes respond to polysaccharide antigens in the presence of IL-1 and IL-6

1 reference

12 December 2020

Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor

1 reference

12 December 2020

IL-12 enhances antibody responses to T-independent polysaccharide vaccines in the absence of T and NK cells

1 reference

12 December 2020

Synthetic oligodeoxynucleotide containing CpG motif induces an anti-polysaccharide type 1-like immune response after immunization of mice with Haemophilus influenzae type b conjugate vaccine

1 reference

12 December 2020

CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen

1 reference

12 December 2020

Role of accessory cells in B cell activation. I. Macrophage presentation of TNP-Ficoll: evidence for macrophage-B cell interaction

1 reference

12 December 2020

Differential responses of B cells from the spleen and lymph node to TNP-Ficoll

1 reference

12 December 2020

Marginal zone macrophages and their role in the immune response against T-independent type 2 antigens: modulation of the cells with specific antibody

1 reference

12 December 2020

Antibody response to pneumococcal polysaccharide vaccine in young, adult and old mice

1 reference

12 December 2020

CpG oligodeoxynucleotides can circumvent the Th2 polarization of neonatal responses to vaccines but may fail to fully redirect Th2 responses established by neonatal priming

1 reference

12 December 2020