A novel nonnucleoside inhibitor specifically targets cytomegalovirus DNA maturation via the UL89 and UL56 gene products (Q28348812)

3 July 2017

title

A novel nonnucleoside inhibitor specifically targets cytomegalovirus DNA maturation via the UL89 and UL56 gene products (English)

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3 July 2017

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8

H D Klenk

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3 July 2017

I Buerger

1

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3 July 2017

J Reefschlaeger

2

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3 July 2017

W Bender

3

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3 July 2017

P Eckenberg

4

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3 July 2017

A Popp

5

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3 July 2017

O Weber

6

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3 July 2017

S Graeper

7

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3 July 2017

H Ruebsamen-Waigmann

9

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3 July 2017

S Hallenberger

10

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3 July 2017

language of work or name

English

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publication date

1 October 2001

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3 July 2017

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3 July 2017

volume

75

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3 July 2017

issue

19

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3 July 2017

page(s)

9077-9086

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Resistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56

3 July 2017

cites work

1 reference

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Inhibition of human cytomegalovirus DNA maturation by a benzimidazole ribonucleoside is mediated through the UL89 gene product

20 March 2017

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Cloning and mutagenesis of a herpesvirus genome as an infectious bacterial artificial chromosome

20 March 2017

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Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region

20 March 2017

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Inhibition of cellular DNA polymerase alpha and human cytomegalovirus-induced DNA polymerase by the triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine

20 March 2017

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Foscarnet. A review of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with cytomegalovirus retinitis

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20 March 2017

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Cloning of the human cytomegalovirus (HCMV) genome as an infectious bacterial artificial chromosome in Escherichia coli: a new approach for construction of HCMV mutants.

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Physical and functional interactions between the herpes simplex virus UL15 and UL28 DNA cleavage and packaging proteins

29 September 2017

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Significance of cytomegalovirus for long-term survival after orthotopic liver transplantation: a prospective derivation and validation cohort analysis.

29 September 2017

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Herpes simplex virus type 1 cleavage and packaging proteins UL15 and UL28 are associated with B but not C capsids during packaging

29 September 2017

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Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments

29 September 2017

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The herpes simplex virus type 1 cleavage/packaging protein, UL32, is involved in efficient localization of capsids to replication compartments

29 September 2017

1 reference

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The gene product of human cytomegalovirus open reading frame UL56 binds the pac motif and has specific nuclease activity.

29 September 2017

1 reference

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The product of the herpes simplex virus type 1 UL25 gene is required for encapsidation but not for cleavage of replicated viral DNA.

29 September 2017

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Versatile insertion plasmids for targeted genome manipulations in bacteria: isolation, deletion, and rescue of the pathogenicity island LEE of the Escherichia coli O157:H7 genome

29 September 2017

1 reference

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The U(L)15 gene of herpes simplex virus type 1 contains within its second exon a novel open reading frame that is translated in frame with the U(L)15 gene product

29 September 2017

1 reference

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Characterization of ICP6::lacZ insertion mutants of the UL15 gene of herpes simplex virus type 1 reveals the translation of two proteins

29 September 2017

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The herpes simplex virus type 1 UL6 protein is essential for cleavage and packaging but not for genomic inversion

29 September 2017

1 reference

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A preclinical and clinical overview of the nucleotide-based antiviral agent cidofovir (HPMPC).

29 September 2017

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29 September 2017

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DNA packaging and cutting by phage terminases: control in phage T4 by a synaptic mechanism

29 September 2017

1 reference

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Defined large-scale alterations of the human cytomegalovirus genome constructed by cotransfection of overlapping cosmids

29 September 2017

1 reference

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Isolation and characterization of herpes simplex virus type 1 mutants defective in the UL6 gene

29 September 2017

1 reference

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Double resistance to ganciclovir and foscarnet of four human cytomegalovirus strains recovered from AIDS patients

29 September 2017

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Herpes simplex virus type 1 DNA cleavage and encapsidation require the product of the UL28 gene: isolation and characterization of two UL28 deletion mutants

29 September 2017

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"The end of innocence" revisited: resistance of herpesviruses to antiviral drugs

29 September 2017

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Analysis and mapping of a family of 3'-coterminal transcripts containing coding sequences for human cytomegalovirus open reading frames UL93 through UL99.

29 September 2017

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Molecular cloning and physical mapping of murine cytomegalovirus DNA

29 September 2017

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Replication of herpesvirus DNA. V. Maturation of concatemeric DNA of pseudorabies virus to genome length is related to capsid formation

29 September 2017

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The alpha sequence of the cytomegalovirus genome functions as a cleavage/packaging signal for herpes simplex virus defective genomes

29 September 2017

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29 September 2017

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Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169.

29 September 2017

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High prevalence of latently present cytomegalovirus in arterial walls of patients suffering from grade III atherosclerosis

29 September 2017

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Bacteriophage lambda DNA maturation and packaging

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114476

Replication of herpesvirus DNA IV: Analysis of concaterners

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114476

Structure and assembly of the virion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114476

Pyrophosphate analogues as inhibitors of DNA polymerases of cytomegalovirus, herpes simplex virus and cellular origin

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114476

The herpes simplex virus UL33 gene product is required for the assembly of full capsids

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114476

Channel catfish virus: A new type of herpesvirus

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114476

The causes of death in patients with human immunodeficiency virus infection: a clinical and pathologic study with emphasis on the role of pulmonary diseases

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114476

Intracellular metabolism of the antiherpes agent (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114476

Cloning, overexpression and purification of the terminase proteins gp16 and gp17 of bacteriophage T4. Construction of a defined in-vitro DNA packaging system using purified terminase proteins.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114476

Cohort study of cytomegalovirus infection as a risk factor for carotid intimal-medial thickening, a measure of subclinical atherosclerosis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114476

Identification of the gene product encoded by ORF UL56 of the human cytomegalovirus genome

27 November 2018

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12 December 2020

A novel terminase activity associated with the DNA packaging protein gp17 of bacteriophage T4

1 reference

12 December 2020

Structural analysis of DNA cleaved in vivo by bacteriophage T4 terminase

1 reference

12 December 2020

Structural and functional domains of the large subunit of the bacteriophage T3 DNA packaging enzyme: importance of the C-terminal region in prohead binding

1 reference

12 December 2020

A discontinuous headful packaging model for packaging less than headful length DNA molecules by bacteriophage T4

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12 December 2020

Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy

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12 December 2020

Ocular manifestations of HIV infection

1 reference

12 December 2020

Genetic analysis of a clinical isolate of human cytomegalovirus exhibiting resistance against both ganciclovir and cidofovir

1 reference

12 December 2020

Biochemical characterization of an ATPase activity associated with the large packaging subunit gp17 from bacteriophage T4

1 reference

12 December 2020

10.1128/JVI.75.19.9077-9086.2001

Identifiers

DOI

1 reference

3 July 2017

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1 reference