Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients (Q28354167)

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English	Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients	scientific article

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Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients (English)

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author name string

H K Roh

1

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J Y Chung

2

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D Y Oh

3

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C S Park

4

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J O Svensson

5

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M L Dahl

6

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L Bertilsson

7

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language of work or name

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publication date

September 2001

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British Journal of Clinical Pharmacology

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52

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3

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265-71

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The effect of benztropine on haloperidol-induced dystonia, clinical efficacy and pharmacokinetics: a prospective, double-blind trial

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

20 March 2017

Involvement of human cytochrome P450 3A4 in reduced haloperidol oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

29 September 2017

Characterization of the cytochrome P450 isoenzymes involved in the in vitro N-dealkylation of haloperidol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

29 September 2017

Involvement of CYP3A4 and CYP2D6 in the metabolism of haloperidol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

29 September 2017

Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

29 September 2017

The relationship between serum concentration and therapeutic effect of haloperidol in patients with acute schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

2 June 2018

Formation of pyridinium species of haloperidol in human liver and brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

2 June 2018

Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

2 June 2018

Interconversion between haloperidol and reduced haloperidol in healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

2 June 2018

Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

2 June 2018

Isolation and Identification of a Metabolite of Haloperidol

1 reference

https://api.crossref.org/works/10.1046%2FJ.0306-5251.2001.01437.X

21 January 2018

Polymorphic oxidation of sparteine and debrisoquine: Related pharmacogenetic entities

1 reference

https://api.crossref.org/works/10.1046%2FJ.0306-5251.2001.01437.X

21 January 2018

Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification

1 reference

https://api.crossref.org/works/10.1046%2FJ.0306-5251.2001.01437.X

21 January 2018

Evidence for a new variant CYP2D6 allele CYP2D6J in a Japanese population associated with lower in vivo rates of sparteine metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

27 November 2018

Haloperidol disposition is dependent on debrisoquine hydroxylation phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

27 November 2018

Haloperidol disposition is dependent on the debrisoquine hydroxylation phenotype: increased plasma levels of the reduced metabolite in poor metabolizers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014539

27 November 2018

Quantitative analysis of two pyridinium metabolites of haloperidol in patients with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

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Nonlinear relationship between circulating concentrations of reduced haloperidol and haloperidol: evaluation of possible mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

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PCR-based genotyping for duplicated and deleted CYP2D6 genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

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Debrisoquine and S-mephenytoin hydroxylation phenotypes and genotypes in a Korean population

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the CYP2D6 genotype on the steady-state plasma concentrations of haloperidol and reduced haloperidol in Japanese schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the CYP2D6*10 allele on the steady-state plasma concentrations of haloperidol and reduced haloperidol in Japanese patients with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pronounced differences in the dispositon of clomipramine between Japanese and Swedish patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-equipotent doses partly explain differences among antipsychotics - implications of PET studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

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Haloperidol and reduced haloperidol plasma levels in selected schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

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HALOPERIDOL METABOLISM AND ANTIPSYCHOTIC EFFECT IN SCHIZOPHRENIA

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interconversion between haloperidol and reduced haloperidol in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol reductase in human and guinea pig livers

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of antisera in the isolation of human specific conjugates of haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of the sparteine/debrisoquine oxidation polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haloperidol reduction can be assayed in human red blood cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population

1 reference

https://pubmed.ncbi.nlm.nih.gov/11560558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.0306-5251.2001.01437.X

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