Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent (Q28360679)

1

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J L Montiel

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V Mendoza

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G Mendoza-Hernández

4

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F López-Casillas

TGFbeta signaling in growth control, cancer, and heritable disorders

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language of work or name

English

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publication date

1 April 2001

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published in

Biochemical Journal

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volume

355

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issue

Pt 1

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page(s)

215-22

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cites work

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Betaglycan binds inhibin and can mediate functional antagonism of activin signalling

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Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites

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Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta

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Membrane-anchored and soluble forms of betaglycan, a polymorphic proteoglycan that binds transforming growth factor-beta

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Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure

20 March 2017

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Expression cloning and characterization of the TGF-beta type III receptor

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Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-beta receptor system

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TGF beta signals through a heteromeric protein kinase receptor complex

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Murine betaglycan primary structure, expression and glycosaminoglycan attachment sites

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The transforming growth factor beta receptors types I, II, and III form hetero-oligomeric complexes in the presence of ligand

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Purification of the transforming growth factor-beta (TGF-beta) binding proteoglycan betaglycan

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Transforming growth factor beta contributes to progressive diabetic nephropathy

29 September 2017

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Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice

29 September 2017

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29 September 2017

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29 September 2017

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Expression of transforming growth factor beta type III receptor suppresses tumorigenicity of human breast cancer MDA-MB-231 cells

29 September 2017

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Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung

29 September 2017

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29 September 2017

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The recombinant proregion of transforming growth factor beta1 (latency-associated peptide) inhibits active transforming growth factor beta1 in transgenic mice.

29 September 2017

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29 September 2017

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29 September 2017

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TGF-beta receptors and actions

29 September 2017

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Mapping of the ligand binding domain of the transforming growth factor beta receptor type III by deletion mutagenesis

29 September 2017

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The types II and III transforming growth factor-beta receptors form homo-oligomers

29 September 2017

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Transforming growth factor-beta in disease: the dark side of tissue repair

29 September 2017

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Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

29 September 2017

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TGF-beta in kidney fibrosis: a target for gene therapy

29 September 2017

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Betaglycan presents ligand to the TGF beta signaling receptor.

2 June 2018

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Membrane binding characteristics of two forms of transforming growth factor-beta.

2 June 2018

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The oligosaccharides of influenza virus hemagglutinin expressed in insect cells by a baculovirus vector

2 June 2018

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Distinct transforming growth factor-beta (TGF-beta) receptor subsets as determinants of cellular responsiveness to three TGF-beta isoforms.

2 June 2018

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Control of scarring in adult wounds by neutralising antibody to transforming growth factor beta

2 June 2018

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Hepatic fibrosis as wound repair: a progress report

2 June 2018

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Betaglycan has multiple binding sites for transforming growth factor-beta 1.

27 November 2018

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Subtypes of betaglycan and of type I and type II transforming growth factor‐β (TGF‐β) receptors with different affinities for TGF‐β1 and TGF‐β2 are exhibited by human placental trophoblast cells

27 November 2018

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12 December 2020

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

1 reference

12 December 2020

Expression of transforming growth factor type III receptor in vascular endothelial cells increases their responsiveness to transforming growth factor beta 2

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12 December 2020

Analysis of the interaction between two TGF-beta-binding proteins and three TGF-beta isoforms using surface plasmon resonance

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12 December 2020

Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice

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12 December 2020

Role of the Juxtamembrane Domains of the Transforming Growth Factor-α Precursor and the β-Amyloid Precursor Protein in Regulated Ectodomain Shedding

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12 December 2020

Subunit structure of a high-affinity receptor for type beta-transforming growth factor. Evidence for a disulfide-linked glycosylated receptor complex

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Chemical deglycosylation of glycoproteins

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