TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1 (Q28361340)

2

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E Kremmer

3

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T W Mak

4

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H Engelmann

5

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W Hammerschmidt

6

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A Kieser

Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling

7

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language of work or name

English

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publication date

15 October 2001

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published in

The EMBO Journal

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volume

20

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page(s)

5678-91

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issue

20

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cites work

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The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation

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The Epstein-Barr virus LMP1 amino acid sequence that engages tumor necrosis factor receptor associated factors is critical for primary B lymphocyte growth transformation

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29 September 2017

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29 September 2017

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The Epstein-Barr virus LMP1 cytoplasmic carboxy terminus is essential for B-lymphocyte transformation; fibroblast cocultivation complements a critical function within the terminal 155 residues.

29 September 2017

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29 September 2017

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29 September 2017

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A vector that replicates as a plasmid and can be efficiently selected in B-lymphoblasts transformed by Epstein-Barr virus

29 September 2017

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29 September 2017

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Epstein-Barr virus latent membrane protein-1 (LMP1) C-terminus activation region 2 (CTAR2) maps to the far C-terminus and requires oligomerisation for NF-kappaB activation

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Transducing signals of life and death

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The Epstein-Barr virus latent membrane protein-1 (LMP1) mediates activation of NF-kappa B and cell surface phenotype via two effector regions in its carboxy-terminal cytoplasmic domain.

2 June 2018

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An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.

2 June 2018

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Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virus

2 June 2018

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Monoclonal antibodies to the latent membrane protein of Epstein-Barr virus reveal heterogeneity of the protein and inducible expression in virus-transformed cells

2 June 2018

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Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death

2 June 2018

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The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B

2 June 2018

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Assaying the activity of kinases regulated by LMP1.

2 June 2018

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Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses

27 November 2018

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Signal transduction from the Epstein-Barr virus LMP-1 transforming protein

27 November 2018

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Localization of the major NF-kappaB-activating site and the sole TRAF3 binding site of LMP-1 defines two distinct signaling motifs

27 November 2018

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12 December 2020

Differential role for p38 mitogen-activated protein kinase in regulating CD40-induced gene expression in dendritic cells and B cells

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12 December 2020

Different Mitogen-activated Protein Kinase Signaling Pathways Cooperate to Regulate Tumor Necrosis Factor α Gene Expression in T Lymphocytes

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12 December 2020

The EBV transforming protein, latent membrane protein 1, mimics and cooperates with CD40 signaling in B lymphocytes

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12 December 2020

Identifiers

DOI

10.1093/EMBOJ/20.20.5678

1 reference

3498700

3498700

1 reference

1 reference

1 reference