An SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathway (Q28361516)

1

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S Funamoto

2

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M Fukuzawa

3

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J Meisenhelder

4

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T Araki

5

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T Abe

6

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R Meili

7

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T Hunter

8

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J Williams

9

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R A Firtel

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

10

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language of work or name

English

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publication date

15 March 2001

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published in

Genes & Development

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volume

15

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issue

6

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page(s)

687-98

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cites work

1 reference

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Signaling by distinct classes of phosphoinositide 3-kinases

20 March 2017

1 reference

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A cell's sense of direction

20 March 2017

2 references

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20 March 2017

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Signalling through phosphoinositide 3-kinases: the lipids take centre stage

29 September 2017

1 reference

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Mechanism of activation of protein kinase B by insulin and IGF-1

20 March 2017

1 reference

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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

20 March 2017

1 reference

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Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids

20 March 2017

1 reference

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Coronin, an actin binding protein of Dictyostelium discoideum localized to cell surface projections, has sequence similarities to G protein beta subunits

20 March 2017

1 reference

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Role of translocation in the activation and function of protein kinase B

20 March 2017

1 reference

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Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

20 March 2017

1 reference

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

20 March 2017

1 reference

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Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products

7 April 2017

1 reference

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The molecular genetics of chemotaxis: sensing and responding to chemoattractant gradients

29 September 2017

1 reference

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Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

29 September 2017

1 reference

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Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

29 September 2017

1 reference

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Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

29 September 2017

1 reference

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Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages

29 September 2017

1 reference

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PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis

29 September 2017

1 reference

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Phosphoinositide binding domains: embracing 3-phosphate

29 September 2017

1 reference

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Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

The role of phosphoinositide 3-kinase lipid products in cell function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

The small Mr Ras-like GTPase Rap1 and the phospholipase C pathway act to regulate phagocytosis in Dictyostelium discoideum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Regulation of actin polymerization in cell-free systems by GTPgammaS and Cdc42

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Inactivation of two Dictyostelium discoideum genes, DdPIK1 and DdPIK2, encoding proteins related to mammalian phosphatidylinositide 3-kinases, results in defects in endocytosis, lysosome to postlysosome transport, and actin cytoskeleton organization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Classification of tyrosine kinases from Dictyostelium discoideum with two distinct, complete or incomplete catalytic domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

A novel Akt/PKB-related kinase is essential for morphogenesis in Dictyostelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Leukocyte polarization in cell migration and immune interactions

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

The Dictyostelium MAP kinase kinase DdMEK1 regulates chemotaxis and is essential for chemoattractant-mediated activation of guanylyl cyclase

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

SH2 signaling in a lower eukaryote: a STAT protein that regulates stalk cell differentiation in dictyostelium.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

The Dictyostelium dual-specificity kinase splA is essential for spore differentiation.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

A transformation vector for dictyostelium discoideum with a new selectable marker bsr.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Chemoattractant-controlled accumulation of coronin at the leading edge of Dictyostelium cells monitored using a green fluorescent protein-coronin fusion protein.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Membrane binding of myristylated peptides corresponding to the NH2 terminus of Src.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312652

Transmembrane signaling in Dictyostelium

27 November 2018

1 reference

12 December 2020

Stress-induced tyrosine phosphorylation of actin in Dictyostelium cells and localization of the phosphorylation site to tyrosine-53 adjacent to the DNase I binding loop

1 reference

12 December 2020

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

1 reference

12 December 2020

G-Protein-coupled receptors and Fcgamma-receptors mediate activation of Akt/protein kinase B in human phagocytes

1 reference

12 December 2020

G protein signaling events are activated at the leading edge of chemotactic cells

1 reference

12 December 2020

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

1 reference

12 December 2020

release_telxunzghndtrbwb4f3kgc2noq

Identifiers

DOI

10.1101/GAD.871001

0 references

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/telxunzghndtrbwb4f3kgc2noq

24 November 2022