Substance P antagonist (CP-96,345) inhibits HIV-1 replication in human mononuclear phagocytes (Q28361559)

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W Z Ho

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G X Zhan

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Y Yi

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R G Collman

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S D Douglas

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

27 March 2001

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published in

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volume

98

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issue

7

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page(s)

3970-5

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cites work

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A new classification for HIV-1

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Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

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Role of CXCR4 in cell-cell fusion and infection of monocyte-derived macrophages by primary human immunodeficiency virus type 1 (HIV-1) strains: two distinct mechanisms of HIV-1 dual tropism.

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Functional analysis of the proximal CCR5 promoter

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CXCR-4 is expressed by primary macrophages and supports CCR5-independent infection by dual-tropic but not T-tropic isolates of human immunodeficiency virus type 1

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Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats.

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Characterization of substance P binding to human monocytes/macrophages

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In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity

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Human lymphocytes express substance P and its receptor

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The kinetics of human immunodeficiency virus reverse transcription are slower in primary human macrophages than in a lymphoid cell line

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Monokine regulation of human immunodeficiency virus-1 expression in a chronically infected human T cell clone

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Substance P production by P388D1 macrophages: a possible autocrine function for this neuropeptide

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Modulation of the mRNAs encoding substance P and its receptor in rat macrophages by LPS

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The neuropeptide substance P activates transcription factor NF-kappa B and kappa B-dependent gene expression in human astrocytoma cells.

2 June 2018

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Enhanced secretion of substance P by cytokine-stimulated rat brain endothelium cultures

28 July 2018

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Evidence of blood-brain barrier alteration and activation in HIV-1 gp120 transgenic mice

21 January 2018

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Identification of a delta isoform of preprotachykinin mRNA in human mononuclear phagocytes and lymphocytes

21 January 2018

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HIV-1 gp120 increases the permeability of rat brain endothelium cultures by a mechanism involving substance P.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.071052298

Substance P modulates human immunodeficiency virus replication in human peripheral blood monocyte-derived macrophages

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.071052298

The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

21 January 2018

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Substance P-induced IL-12 production by murine macrophages.

21 January 2018

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Substance P activates coincident NF-AT- and NF-kappa B-dependent adhesion molecule gene expression in microvascular endothelial cells through intracellular calcium mobilization

27 November 2018

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12 December 2020

Substance P activates NF-kappaB independent of elevations in intracellular calcium in murine macrophages and dendritic cells

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12 December 2020

Purification of human monocytes on gelatin-coated surfaces

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12 December 2020

Effect of neuropeptides on production of inflammatory cytokines by human monocytes

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12 December 2020

The neuropeptide substance P stimulates production of interleukin 1 in human blood monocytes: activated cells are preferentially influenced by the neuropeptide

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12 December 2020

Substance P C-terminal octapeptide analogues augment tumor necrosis factor-alpha release by human blood monocytes and macrophages

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12 December 2020

Isolation of highly purified human blood monocytes for in vitro HIV-1 infection studies of monocyte/macrophages

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12 December 2020

A Potent Nonpeptide Antagonist of the Substance P (NK 1 ) Receptor

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12 December 2020

Immunopathogenesis of HIV infection

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12 December 2020

Detection of substance P immunoreactivity in human peripheral leukocytes

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12 December 2020

Autocrine induction of substance P mRNA and peptide in cultured normal human keratinocytes

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12 December 2020

Substance P augments interleukin-10 and tumor necrosis factor-alpha release by human cord blood monocytes and macrophages

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.071052298

1 reference

release_ddeppgklxjeb7ptvzpxobfig7y

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1250932

1 reference

1 reference

1250932

PubMed publication ID

11274418

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