Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease (Q28361615)

8

object named as

W J Sandborn

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William J. Tremaine

6

object named as

W J Tremaine

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author name string

P W Lowry

1

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C L Franklin

2

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A L Weaver

3

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M G Pike

4

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D C Mays

5

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J J Lipsky

Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide

7

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language of work or name

English

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publication date

November 2001

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published in

Gut

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volume

49

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issue

5

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page(s)

665-70

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cites work

1 reference

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Quality of life: a valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease. Canadian Crohn's Relapse Prevention Trial Study Group

20 March 2017

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Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity

20 March 2017

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Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations

20 March 2017

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Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease

20 March 2017

1 reference

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A reversed phase high performance liquid chromatography approach in determining total red blood cell concentrations of 6-thioguanine, 6-mercaptopurine, methylthioguanine, and methylmercaptopurine in a patient receiving thiopurine therapy

29 September 2017

1 reference

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The clinical pharmacology of 6-mercaptopurine

29 September 2017

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Human liver thiopurine methyltransferase pharmacogenetics: biochemical properties, liver-erythrocyte correlation and presence of isozymes

29 September 2017

1 reference

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Olsalazine and 6-mercaptopurine-related bone marrow suppression: a possible drug-drug interaction

29 September 2017

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6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity

2 June 2018

1 reference

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Sulphasalazine inhibition of thiopurine methyltransferase: possible mechanism for interaction with 6‐mercaptopurine and azathioprine

2 June 2018

1 reference

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Effect of food coadministration on 5-aminosalicylic acid oral suspension bioavailability.

2 June 2018

1 reference

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Assay of 6-thioguanine nucleotide, a major metabolite of azathioprine, 6-mercaptopurine and 6-thioguanine, in human red blood cells

27 November 2018

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12 December 2020

High-performance liquid chromatographic assay for the determination of 5-aminosalicylic acid and acetyl-5-aminosalicylic acid concentrations in endoscopic intestinal biopsy in humans

1 reference

12 December 2020

Mercaptopurine metabolism and risk of relapse in childhood lymphoblastic leukaemia

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12 December 2020

Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis

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12 December 2020

The influence of multiple oral doses of zileuton on the steady-state pharmacokinetics of sulfasalazine and its metabolites, sulfapyridine and N-acetylsulfapyridine

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12 December 2020

The long-term outcome of ulcerative colitis treated with 6-mercaptopurine

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12 December 2020

Patterns of azathioprine metabolites in neutrophils, lymphocytes, reticulocytes, and erythrocytes: relevance to toxicity and monitoring in recipients of renal allografts

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12 December 2020

Balsalazide and azathiprine or 6-mercaptopurine: evidence for a potentially serious drug interaction

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12 December 2020

Lack of effect of intravenous administration on time to respond to azathioprine for steroid-treated Crohn's disease

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12 December 2020

Identifiers

DOI

10.1136/GUT.49.5.665

1 reference

1 reference

1 reference

PubMed publication ID

11600469

1 reference