Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency (Q28365535)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11726526%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

title

Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11726526%20AND%20SRC:MED&resulttype=core&format=json

Eukaryotic translation initiation factor 2 alpha kinase 1

4 December 2019

main subject

1 reference

GOA release 2020-03-11

0 references

3

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4 December 2019

Mark D Fleming

7

1 reference

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4 December 2019

author name string

A P Han

1

1 reference

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4 December 2019

C Yu

2

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4 December 2019

Y Fujiwara

4

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4 December 2019

C Browne

5

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4 December 2019

G Chin

6

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4 December 2019

P Leboulch

8

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4 December 2019

S H Orkin

9

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4 December 2019

J J Chen

10

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4 December 2019

language of work or name

English

0 references

publication date

1 December 2001

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4 December 2019

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4 December 2019

volume

20

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4 December 2019

issue

23

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4 December 2019

page(s)

6909-6918

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A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha

4 December 2019

cites work

1 reference

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Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase

20 March 2017

1 reference

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

20 March 2017

1 reference

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Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

20 March 2017

1 reference

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Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

20 March 2017

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Ribosome association of GCN2 protein kinase, a translational activator of the GCN4 gene of Saccharomyces cerevisiae

20 March 2017

1 reference

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

20 March 2017

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Structure of the EF corner favors deamidation of asparaginyl residues in hemoglobin: the example of Hb La Roche-sur-Yon [beta 81 (EF5) Leu----His]

20 March 2017

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Two heme-binding domains of heme-regulated eukaryotic initiation factor-2alpha kinase. N terminus and kinase insertion

20 March 2017

1 reference

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

20 March 2017

1 reference

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Regulation of hemoglobin synthesis and proliferation of differentiating erythroid cells by heme-regulated eIF-2alpha kinase

20 March 2017

1 reference

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The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage

20 March 2017

1 reference

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Cloning and characterization of cDNA encoding rat hemin-sensitive initiation factor-2 alpha (eIF-2 alpha) kinase. Evidence for multitissue expression

20 March 2017

1 reference

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Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

20 March 2017

1 reference

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Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125753

Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125753

Selenocysteine codons decrease polysome association on endogenous selenoprotein mRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125753

The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125753

Pathophysiology of thrombocytopenia and anemia in mice lacking transcription factor NF-E2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125753

Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice

29 September 2017

1 reference

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Characterization of the hemin-sensitive eukaryotic initiation factor 2alpha kinase from mouse nonerythroid cells

29 September 2017

1 reference

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Removal of erythrocyte membrane iron in vivo ameliorates the pathobiology of murine thalassemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125753

The role of heme in gene expression

29 September 2017

1 reference

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Erythroid expression of the heme-regulated eIF-2 alpha kinase

29 September 2017

1 reference

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The fate of excess β-globin chains within erythropoietic cells in α-thalassaemia 2 trait, α-thalassaemia 1 trait, haemoglobin H disease and haemoglobin Q-H disease: an electron microscope study

29 September 2017

1 reference

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Electron Microscope and High Resolution Autoradiographic Studies of the Erythroblasts in Haemoglobin H Disease

29 September 2017

1 reference

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Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase

29 September 2017

1 reference

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Sequential induction of heme pathway enzymes during erythroid differentiation of mouse Friend leukemia virus-infected cells

29 September 2017

1 reference

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Phosphorylation of initiation factor elF-2 and the control of reticulocyte protein synthesis

29 September 2017

1 reference

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Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.

29 September 2017

1 reference

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Inhibition of protein synthesis in insect cells by baculovirus-expressed heme-regulated eIF-2 alpha kinase.

2 June 2018

1 reference

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Influence of prosthetic groups on protein folding and subunit assembly. Recombination of separated human alpha-and beta-globin chains with heme and alloplex interactions of globin chains with heme-containing subunits.

2 June 2018

1 reference

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Composition of the intra-erythroblastic precipitates in thalassaemia and congenital dyserythropoietic anaemia (CDA): identification of a new type of CDA with intra-erythroblastic precipitates not reacting with monoclonal antibodies to alpha- and bet

2 June 2018

1 reference

12 December 2020

Heme-regulated eIF-2alpha kinase purifies as a hemoprotein

1 reference

12 December 2020

Influence of prosthetic groups on protein folding and subunit assembly. I. Conformational differences between separated human alpha- and beta- globins

1 reference

12 December 2020

Ultrastructural Studies in β-Thalassaemia Major

1 reference

12 December 2020

Observations on the Ultrastructure of Erythropoietic Cells and Reticulum Cells in the Bone Marrow of Patients with Homozygous β-Thalassaemia

1 reference

12 December 2020

Thiazole orange: a new dye for reticulocyte analysis

1 reference

12 December 2020

Disulfide bond formation in the regulation of eIF-2 alpha kinase by heme

1 reference

12 December 2020

Haemoglobin Hammersmith (β 42 (CD1) Phe→Ser)

1 reference

12 December 2020

Biotin labeling as an alternative nonradioactive approach to determination of red cell survival

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/20.23.6909

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11726526%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11726526%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

2 references