High levels of the MDM2 oncogene in paediatric rhabdomyosarcoma cell lines may confer multidrug resistance (Q28366242)

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4 December 2019

title

High levels of the MDM2 oncogene in paediatric rhabdomyosarcoma cell lines may confer multidrug resistance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11742497%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

main subject

multiple drug resistance

0 references

1 reference

3

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4 December 2019

author name string

H A Cocker

1

1 reference

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4 December 2019

S M Hobbs

2

1 reference

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4 December 2019

K Pritchard-Jones

4

1 reference

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4 December 2019

C R Pinkerton

5

1 reference

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4 December 2019

L R Kelland

6

1 reference

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4 December 2019

language of work or name

English

0 references

publication date

1 November 2001

1 reference

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British Journal of Cancer

4 December 2019

published in

1 reference

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4 December 2019

volume

85

1 reference

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4 December 2019

issue

11

1 reference

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4 December 2019

page(s)

1746-1752

1 reference

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Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

4 December 2019

copyright license

start time

27 November 2001

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

The MDM2 C-terminal region binds to TAFII250 and is required for MDM2 regulation of the cyclin A promoter

1 reference

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

20 March 2017

1 reference

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P53 mutation and MDM2 amplification frequency in pediatric rhabdomyosarcoma tumors and cell lines

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363993

Characterization and modulation of drug resistance of human paediatric rhabdomyosarcoma cell lines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363993

Regulation of p53 stability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363993

Development of a bicistronic vector driven by the human polypeptide chain elongation factor 1alpha promoter for creation of stable mammalian cell lines that express very high levels of recombinant proteins

29 September 2017

1 reference

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Wild-type p53 gene increases MDR1 gene expression but decreases drug resistance in an MDR cell line KBV200.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363993

p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents

29 September 2017

1 reference

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mdm2 gene mediates the expression of mdr1 gene and P-glycoprotein in a human glioblastoma cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363993

The MDM2 oncoprotein is overexpressed in rhabdomyosarcoma cell lines and stabilizes wild-type p53 protein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363993

Effects of a new antioestrogen, idoxifene, on cisplatin- and doxorubicin-sensitive and -resistant human ovarian carcinoma cell lines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363993

Expression of the multidrug resistance-associated protein (MRP) gene correlates with amplification and overexpression of the N-myc oncogene in childhood neuroblastoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363993

mdm 2 mRNA expression is associated with survival in ovarian cancer.

29 September 2017

1 reference

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P-glycoprotein expression at diagnosis may not be a primary mechanism of therapeutic failure in childhood rhabdomyosarcoma

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363993

Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood

2 June 2018

1 reference

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Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363993

Role of MDM2 overexpression in doxorubicin resistance of breast carcinoma.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2363993

A 190-kilodalton protein overexpressed in non-P-glycoprotein-containing multidrug-resistant cells and its relationship to the MRP gene.

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1054%2FBJOC.2001.2145

Stabilization of the MDM2 oncoprotein by mutant p53

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11742497

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MDM2 amplification in a primary alveolar rhabdomyosarcoma displaying a t(2;13)(q35;q14)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11742497

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

New multidrug-resistance-reversing drugs, MS-209 and SDZ PSC 833

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11742497

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1054/BJOC.2001.2145

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11742497%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11742497%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11742497%20AND%20SRC:MED&resulttype=core&format=json