Cavities of alpha(1)-antitrypsin that play structural and functional roles (Q28367429)

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J S Maeng

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J P Kocher

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B Lee

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M H Yu

Stabilization of hen egg white lysozyme by a cavity-filling mutation

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language of work or name

English

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publication date

July 2001

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published in

Protein Science

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volume

10

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issue

7

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page(s)

1446-53

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cites work

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The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A

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The interpretation of protein structures: Total volume, group volume distributions and packing density

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Cloning, expression, purification, and biological activity of recombinant native and variant human alpha 1-antichymotrypsins

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Structural and thermodynamic analysis of the packing of two alpha-helices in bacteriophage T4 lysozyme

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20 March 2017

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Role of Lys335 in the metastability and function of inhibitory serpins

29 September 2017

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Partitioning of serpin-proteinase reactions between stable inhibition and substrate cleavage is regulated by the rate of serpin reactive center loop insertion into beta-sheet A.

29 September 2017

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Wild-type alpha 1-antitrypsin is in the canonical inhibitory conformation.

29 September 2017

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Influenza hemagglutinin is spring-loaded by a metastable native conformation

29 September 2017

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Regulation of Drosophila heat shock factor trimerization: global sequence requirements and independence of nuclear localization

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A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism

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29 September 2017

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29 September 2017

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Stabilization of protein structures

29 September 2017

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Conformational stabilities of Escherichia coli RNase HI variants with a series of amino acid substitutions at a cavity within the hydrophobic core.

2 June 2018

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The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

2 June 2018

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Buried waters and internal cavities in monomeric proteins

2 June 2018

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2 June 2018

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2 June 2018

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https://api.crossref.org/works/10.1110%2FPS.840101

Structural basis for serpin inhibitor activity

21 January 2018

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Single amino acid substitutions of alpha 1-antitrypsin that confer enhancement in thermal stability.

21 January 2018

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27 November 2018

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Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

21 January 2018

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12 December 2020

Probing the native strain iin alpha1-antitrypsin

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12 December 2020

Metastability in the inhibitory mechanism of human alpha1-antitrypsin

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12 December 2020

Distribution of the native strain in human alpha 1-antitrypsin and its association with protease inhibitor function

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12 December 2020