pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo (Q28368048)

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English	pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo	scientific article

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scholarly article

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23 October 2019

pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo (English)

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23 October 2019

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23 October 2019

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J J Eron

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23 October 2019

Richard T D'Aquila

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R T D'Aquila

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23 October 2019

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Y K Chow

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23 October 2019

A M Caliendo

3

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23 October 2019

J Videler

4

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23 October 2019

K M Devore

5

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23 October 2019

H A Liebman

7

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23 October 2019

J C Kaplan

8

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23 October 2019

M S Hirsch

9

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23 October 2019

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1 July 1993

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23 October 2019

Antimicrobial Agents and Chemotherapy

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23 October 2019

37

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23 October 2019

7

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23 October 2019

1480-1487

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23 October 2019

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

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20 March 2017

Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

1 reference

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20 March 2017

HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy

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20 March 2017

In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine

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20 March 2017

Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase

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20 March 2017

Two-Drug Combinations of Zidovudine, Didanosine, and Recombinant Interferon- A Inhibit Replication of Zidovudine-Resistant Human Immunodeficiency Virus Type 1 Synergistically In Vitro

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20 March 2017

Molecular targets for AIDS therapy

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20 March 2017

Biological comparison of wild-type and zidovudine-resistant isolates of human immunodeficiency virus type 1 from the same subjects: susceptibility and resistance to other drugs

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20 March 2017

Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine

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20 March 2017

Synergistic inhibition of replication of human immunodeficiency virus type 1, including that of a zidovudine-resistant isolate, by zidovudine and 2',3'-dideoxycytidine in vitro

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20 March 2017

Human immunodeficiency virus type 1 pol gene mutations which cause decreased susceptibility to 2',3'-dideoxycytidine

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20 March 2017

3'-Azido-3'-deoxythymidine resistance suppressed by a mutation conferring human immunodeficiency virus type 1 resistance to nonnucleoside reverse transcriptase inhibitors

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20 March 2017

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

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7 April 2017

The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

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7 April 2017

Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4 and application in a plaque assay

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7 April 2017

Optimal conditions for directly sequencing double-stranded PCR products with sequenase

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29 September 2017

Dynamic changes in HIV-1 quasispecies from azidothymidine (AZT)-treated patients

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29 September 2017

Susceptibility testing by polymerase chain reaction DNA quantitation: a method to measure drug resistance of human immunodeficiency virus type 1 isolates

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29 September 2017

Didanosine and zidovudine resistance patterns in clinical isolates of human immunodeficiency virus type 1 as determined by a replication endpoint concentration assay

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29 September 2017

Reverse transcriptase of human immunodeficiency virus can use either human tRNA(3Lys) or Escherichia coli tRNA(2Gln) as a primer in an in vitro primer-utilization assay

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29 September 2017

Cloning of HTLV-4 and its relation to simian and human immunodeficiency viruses

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2 June 2018

Complete nucleotide sequences of functional clones of the AIDS virus

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2 June 2018

Decreased in vitro susceptibility to zidovudine of HIV isolates obtained from patients with AIDS.

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2 June 2018

The safety and efficacy of zidovudine (AZT) in the treatment of subjects with mildly symptomatic human immunodeficiency virus type 1 (HIV) infection. A double-blind, placebo-controlled trial. The AIDS Clinical Trials Group

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Biochemical studies on the reverse transcriptase and RNase H activities from human immunodeficiency virus strains resistant to 3'-azido-3'-deoxythymidine

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2 June 2018

HIV-1 sensitivity to zidovudine and clinical outcome in children

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Isolation of drug-resistant variants of HIV-1 from patients on long-term zidovudine therapy

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Once-daily administration of 2',3'-dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex. Results of a Phase I trial

1 reference

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Identifiers

10.1128/AAC.37.7.1480

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23 October 2019

1 reference

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23 October 2019

1 reference

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23 October 2019

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