Inhibition of human immunodeficiency virus integrase by bis-catechols (Q28368086)

1

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P L Graham

2

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K LeGrow

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J C Hastings

4

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A Wolfe

5

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S D Young

6

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E A Emini

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D J Hazuda

Antimicrobial Agents and Chemotherapy

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language of work or name

English

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publication date

February 1995

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published in

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volume

39

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issue

2

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page(s)

320-4

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cites work

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Inhibition of HIV-1 integration protein by aurintricarboxylic acid monomers, monomer analogs, and polymer fractions

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Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection

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Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein

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Retroviral DNA integration directed by HIV integration protein in vitro

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Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations.

20 March 2017

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Conserved residues Pro-109 and Asp-116 are required for interaction of the human immunodeficiency virus type 1 integrase protein with its viral DNA substrate.

29 September 2017

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Effect of topoisomerase inhibitors on the in vitro HIV DNA integration reaction

29 September 2017

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Inhibitory effect of the polyanionic drug suramin on the in vitro HIV DNA integration reaction

29 September 2017

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Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex

29 September 2017

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Complementation between HIV integrase proteins mutated in different domains

29 September 2017

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29 September 2017

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Genetic analysis of homomeric interactions of human immunodeficiency virus type 1 integrase using the yeast two-hybrid system

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A novel assay for the DNA strand-transfer reaction of HIV-1 integrase

29 September 2017

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Rapid detection and isolation of covalent DNA/protein complexes: application to topoisomerase I and II.

29 September 2017

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Biochemical characterization of topoisomerase I purified from avian erythrocytes

29 September 2017

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Retroviral DNA integration: Structure of an integration intermediate

29 September 2017

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A consensus sequence for cleavage by vertebrate DNA topoisomerase II.

29 September 2017

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Topoisomerase-targeting antitumor drugs

29 September 2017

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The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration

29 September 2017

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Integration of retroviral DNA.

29 September 2017

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Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

29 September 2017

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Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex.

29 September 2017

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Substrate specificity of recombinant human immunodeficiency virus integrase protein

29 September 2017

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HIV protease: a novel chemotherapeutic target for AIDS.

29 September 2017

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Human immunodeficiency virus integrase protein requires a subterminal position of its viral DNA recognition sequence for efficient cleavage

29 September 2017

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Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

29 September 2017

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Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomyces cerevisiae

29 September 2017

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Genetics of retroviral integration

29 September 2017

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Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells

29 September 2017

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Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro

29 September 2017

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The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

29 September 2017

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Retroviral integrase functions as a multimer and can turn over catalytically

2 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162534

The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro.

2 June 2018

1 reference

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Structural implications of spectroscopic characterization of a putative zinc finger peptide from HIV-1 integrase

2 June 2018

1 reference

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Cleavage of DNA by mammalian DNA topoisomerase II

2 June 2018

1 reference

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Single-strand DNA cleavages by eukaryotic topoisomerase II

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7726489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structure of the termini of DNA intermediates in the integration of retroviral DNA: dependence on IN function and terminal DNA sequence

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7726489